Projects per year
Personal profile
Research Interests
Corneal pathobiology, Keratoconus, Diabetic Keratopathy, Sphingolipids, and 3D bioprinting
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Area of Expertise
Dr Karamichos research aims to discover, develop, and deliver novel therapies for the treatment of corneal trauma, diseases, and dystrophies. Dr Karamichos and team focus part of their work on Keratoconus disease where they are working on novel biomarkers and delineating the role of sex hormones during the onset and progression of the disease. Dr Karamichos is also investigating the role of sphingolipids in corneal wound healing, using complementary in vitro and in vivo models. Other areas of investigation are focused on diabetic keratopathy and the application of bioengineering for corneal transplantation.
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Collaborations and top research areas from the last five years
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The Intimate Interplay Between
Karamichos, D. (PI), Cunningham, R. (CoI) & Nandy, R. (CoI)
1/09/23 → 31/01/27
Project: Research
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A Novel Pathogenic Pathway for
Karamichos, D. (PI) & Nandy, R. (CoI)
1/01/23 → 31/12/27
Project: Research
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Mechanisms of collagen crosslinking in diabetes and keratoconus
McKay, T. B., Priyadarsini, S. & Karamichos, D., Oct 2019, In: Cells. 8, 10, 1239.Research output: Contribution to journal › Review article › peer-review
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Systemic and ocular associations of Keratoconus
Hefley, B. S., Ali, A. A., Bhattacharya, P., Hjortdal, J., Walker, M. K. & Karamichos, D., 2024, In: Expert Review of Ophthalmology. 19, 5, p. 379-391 13 p.Research output: Contribution to journal › Review article › peer-review
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Establishment of a 3D In vitro model to accelerate the development of human therapies against corneal diabetes
Priyadarsini, S., Sarker-Nag, A., Rowsey, T. G., Ma, J. X. & Karamichos, D., Dec 2016, In: PLoS ONE. 11, 12, e0168845.Research output: Contribution to journal › Article › peer-review
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The use of human cornea organotypic cultures to study herpes simplex virus type 1 (HSV-1)-induced inflammation
Drevets, P., Chucair-Elliott, A., Shrestha, P., Jinkins, J., Karamichos, D. & Carr, D. J. J., 22 Oct 2015, In: Graefe's Archive for Clinical and Experimental Ophthalmology. 253, 10, p. 1721-1728 8 p.Research output: Contribution to journal › Article › peer-review
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Prospective Observational Study Evaluating Systemic Hormones and Corneal Crosslinking Effects in Keratoconus
Van, L., Bennett, S., Nicholas, S. E., Hjortdal, J., McKay, T. B. & Karamichos, D., 1 Mar 2024, In: Ophthalmology Science. 4, 2, 100364.Research output: Contribution to journal › Article › peer-review