Zinc allosterically modulates antagonist binding to cloned D₁ and D₂ dopamine receptors

Keyphrases

• Allosteric Modulation 12%
• Atomic Scale 12%
• Binding Properties 12%
• D1 Dopamine Receptor 100%
• D2 Dopamine Receptor 100%
• Dissociation Constant 12%
• Dissociation Rate 12%
• Dopamine Receptor 50%
• Dopamine Receptor Antagonist 12%
• Dose Effect 25%
• Ligand Affinity 12%
• Ligand Binding 12%
• Low Affinity 12%
• Noble Gases 12%
• Radioligand Binding 12%
• Receptor-interacting Protein Kinase 1 (RIPK1) 12%
• Reversible Inhibition 12%
• SCH23390 12%
• Selective Antagonist 12%
• Specific Binding 12%
• Subtype-specific 12%
• Two-state 12%
• Zinc 100%
• Zinc Inhibition 25%
• Zn2+ 12%

Pharmacology, Toxicology and Pharmaceutical Science

• Dopamine 1 Receptor 100%
• Dopamine Receptor 100%
• Dopamine Receptor Blocking Agent 25%
• Dopamine Receptor D2 100%
• Ethylenediaminetetraacetic Acid 25%
• Inert Gas 25%
• Radioligand 25%
• Receptor 25%
• Receptor Protein 25%
• Transition Element 25%
• Zinc Ion 25%

Biochemistry, Genetics and Molecular Biology

• Dissociation Constant 20%
• Dopamine Antagonist 20%
• Dopamine Receptor 80%
• Dopamine Receptor D1 100%
• Dopamine Receptor D2 100%
• Ligand Binding 20%
• Radioligand 20%
• SCH 23390 20%
• Zinc 100%