Zacopride

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Zacopride is used in its tritiated form to label 5-HT3 receptors. It is a competitive antagonist used to label both homomeric 5-HT3A receptors and heteromeric 5-HT3A/B receptors. The (S) enantiomer is more selective than the (R) enantiomer. It has been used extensively to assess the roles of the 5-HT3 receptor in behavioral models, such as drug discrimination, anxiety, and cognition. It has been used to evaluate the role of the 5-HT3 receptor in emesis and abdominal contractions. © 2007

Original languageEnglish
Title of host publicationxPharm
Subtitle of host publicationThe Comprehensive Pharmacology Reference
PublisherElsevier Inc.
Pages1-2
Number of pages2
ISBN (Print)9780080552323
DOIs
StatePublished - 1 Jan 2007

Fingerprint Dive into the research topics of 'Zacopride'. Together they form a unique fingerprint.

  • Cite this

    Machu, T. (2007). Zacopride. In xPharm: The Comprehensive Pharmacology Reference (pp. 1-2). Elsevier Inc.. https://doi.org/10.1016/B978-008055232-3.62872-7