Working towards implementation of whole genome mitochondrial DNA sequencing into routine casework

Jennifer D. Churchill, Dixie Peters, Christina Capt, Christina Strobl, Walther Parson, Bruce Budowle

Research output: Contribution to journalArticle

5 Scopus citations

Abstract

Massively parallel sequencing (MPS) technologies offer opportunities to expand forensic mitochondrial DNA (mtDNA) typing capabilities affording higher resolution, an increase in discrimination power, and potentially enabling mixture interpretation. Additionally, improvements to MPS technologies and workflows have made implementation into forensic genetic laboratories increasingly more feasible. Following initial successful studies with the Precision ID mtDNA Whole Genome Panel, the process of internal validation and implementation of whole genome mtDNA sequencing began in our Missing Persons and Forensic Casework Units.

Original languageEnglish
Pages (from-to)e388-e389
JournalForensic Science International: Genetics Supplement Series
Volume6
DOIs
StatePublished - Dec 2017

Keywords

  • Implementation
  • Ion S5
  • Massively parallel sequencing
  • Mitochondrial DNA

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