Use of combined frequencies for RFLP and PCR based loci in determining match probability

Christine S. Tomsey, Christopher J. Basten, Bruce Budowle, Beth Ann Giles, Scott Ermlick, Sarah Gotwald

Research output: Contribution to journalArticle

2 Scopus citations

Abstract

Statistical analysis was performed on a subset of the Pennsylvania State Police Caucasian, African American and Hispanic database for the purpose of determining Hardy-Weinberg equilibrium and associations across the RFLP loci D1S7, D2S44, D4S139, D5S110, D10S28 and D17S79 and the PCR-based loci HLA- DQA1, LDLR, GYPA, HBGG, D7S8 and Gc. Overall, the statistical results are consistent with a population in equilibrium both within and between loci. The assumption for independence is valid.

Original languageEnglish
Pages (from-to)385-388
Number of pages4
JournalJournal of Forensic Sciences
Volume44
Issue number2
DOIs
StatePublished - Mar 1999

Keywords

  • D10S28
  • D17S79
  • D1S7
  • D2S44
  • D4S139
  • D5S110
  • D7S8
  • DNA typing
  • Forensic science
  • GYPA
  • Gc
  • HBGG
  • HLA- DQA1
  • Hardy-Weinberg equilibrium
  • Independence
  • LDLR
  • Linkage equilibrium
  • Polymerase chain reaction
  • Population genetics
  • Restriction fragment length polymorphism

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