Use of combined frequencies for RFLP and PCR based loci in determining match probability

Christine S. Tomsey; Christopher J. Basten; Bruce Budowle; Beth Ann Giles; Scott Ermlick; Sarah Gotwald

doi:10.1520/jfs14469j

Use of combined frequencies for RFLP and PCR based loci in determining match probability

Christine S. Tomsey, Christopher J. Basten, Bruce Budowle, Beth Ann Giles, Scott Ermlick, Sarah Gotwald

Center for Human ID

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Abstract

Statistical analysis was performed on a subset of the Pennsylvania State Police Caucasian, African American and Hispanic database for the purpose of determining Hardy-Weinberg equilibrium and associations across the RFLP loci D1S7, D2S44, D4S139, D5S110, D10S28 and D17S79 and the PCR-based loci HLA- DQA1, LDLR, GYPA, HBGG, D7S8 and Gc. Overall, the statistical results are consistent with a population in equilibrium both within and between loci. The assumption for independence is valid.

Original language	English
Pages (from-to)	385-388
Number of pages	4
Journal	Journal of Forensic Sciences
Volume	44
Issue number	2
DOIs	https://doi.org/10.1520/jfs14469j
State	Published - Mar 1999

Keywords

D10S28
D17S79
D1S7
D2S44
D4S139
D5S110
D7S8
DNA typing
Forensic science
GYPA
Gc
HBGG
HLA- DQA1
Hardy-Weinberg equilibrium
Independence
LDLR
Linkage equilibrium
Polymerase chain reaction
Population genetics
Restriction fragment length polymorphism

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10.1520/jfs14469j

Cite this

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title = "Use of combined frequencies for RFLP and PCR based loci in determining match probability",

abstract = "Statistical analysis was performed on a subset of the Pennsylvania State Police Caucasian, African American and Hispanic database for the purpose of determining Hardy-Weinberg equilibrium and associations across the RFLP loci D1S7, D2S44, D4S139, D5S110, D10S28 and D17S79 and the PCR-based loci HLA- DQA1, LDLR, GYPA, HBGG, D7S8 and Gc. Overall, the statistical results are consistent with a population in equilibrium both within and between loci. The assumption for independence is valid.",

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author = "Tomsey, {Christine S.} and Basten, {Christopher J.} and Bruce Budowle and Giles, {Beth Ann} and Scott Ermlick and Sarah Gotwald",

year = "1999",

month = mar,

doi = "10.1520/jfs14469j",

language = "English",

volume = "44",

pages = "385--388",

journal = "Journal of forensic sciences",

issn = "0022-1198",

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T1 - Use of combined frequencies for RFLP and PCR based loci in determining match probability

AU - Tomsey, Christine S.

AU - Basten, Christopher J.

AU - Budowle, Bruce

AU - Giles, Beth Ann

AU - Ermlick, Scott

AU - Gotwald, Sarah

PY - 1999/3

Y1 - 1999/3

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AB - Statistical analysis was performed on a subset of the Pennsylvania State Police Caucasian, African American and Hispanic database for the purpose of determining Hardy-Weinberg equilibrium and associations across the RFLP loci D1S7, D2S44, D4S139, D5S110, D10S28 and D17S79 and the PCR-based loci HLA- DQA1, LDLR, GYPA, HBGG, D7S8 and Gc. Overall, the statistical results are consistent with a population in equilibrium both within and between loci. The assumption for independence is valid.

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KW - D4S139

KW - D5S110

KW - D7S8

KW - DNA typing

KW - Forensic science

KW - GYPA

KW - Gc

KW - HBGG

KW - HLA- DQA1

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KW - Independence

KW - LDLR

KW - Linkage equilibrium

KW - Polymerase chain reaction

KW - Population genetics

KW - Restriction fragment length polymorphism

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SP - 385

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IS - 2

ER -

Use of combined frequencies for RFLP and PCR based loci in determining match probability

Abstract

Keywords

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