Treatment of hypertension and diabetes mellitus in patients with chronic kidney disease: A review

Rafia Sultana Rasu, Tonya Crawford, Harold J. Manley, Rajesh Balkrishnan

Research output: Contribution to journalReview article

7 Scopus citations


Hypertension and diabetes mellitus are the two leading causes of chronic kidney disease (CKD). The purpose of this paper is to provide an overview of the present pharmacologic and adverse events involved in the treatment of hypertension and diabetes mellitus in patients with CKD. Proper management of hypertension and diabetes mellitus, a common co-morbidity associated with CKD, would slow the progression of kidney disease and reduce healthcare expenditures. Awareness of potential side effects due to the medications or renal insufficiency could prevent unnecessary harm to the patient and provide cost-containment. Active involvement of all healthcare team members can reduce progression of CKD and improve quality of life outcomes in CKD patients.

Original languageEnglish
Pages (from-to)2543-2551
Number of pages9
JournalExpert Opinion on Pharmacotherapy
Issue number15
Publication statusPublished - 1 Oct 2007



  • ACE-I
  • ARB
  • Chronic kidney disease
  • Costs
  • Diabetes mellitus
  • Hypertension
  • Quality of life

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