TY - JOUR
T1 - Treatment of active tuberculosis
T2 - Challenges and prospects
AU - Sahbazian, Behzad
AU - Weis, Stephen E.
PY - 2005/6
Y1 - 2005/6
N2 - Insights gained from studies done by the TBTC have resulted in major changes in the recommendations for drug therapy of tuberculosis in HIV-infected and noninfected individuals [1-5]. Although the goals for the treatment of tuberculosis remain the same, these advances require that tuberculosis drug therapy now be more individualized. Treatment regimens are based on a patient's risk profile based on a combination of hematologic, microbiologic, clinical, and radiographic findings [6]. Although they are more complicated than the previous guidelines, they allow treatment to be refined so that it can be extended in patients at high risk for treatment failure and allow shorter, more convenient treatment regimens in patients who can be identified as being at very low risk for failure [2].
AB - Insights gained from studies done by the TBTC have resulted in major changes in the recommendations for drug therapy of tuberculosis in HIV-infected and noninfected individuals [1-5]. Although the goals for the treatment of tuberculosis remain the same, these advances require that tuberculosis drug therapy now be more individualized. Treatment regimens are based on a patient's risk profile based on a combination of hematologic, microbiologic, clinical, and radiographic findings [6]. Although they are more complicated than the previous guidelines, they allow treatment to be refined so that it can be extended in patients at high risk for treatment failure and allow shorter, more convenient treatment regimens in patients who can be identified as being at very low risk for failure [2].
UR - http://www.scopus.com/inward/record.url?scp=17044366978&partnerID=8YFLogxK
U2 - 10.1016/j.ccm.2005.02.011
DO - 10.1016/j.ccm.2005.02.011
M3 - Review article
C2 - 15837110
AN - SCOPUS:17044366978
VL - 26
SP - 273
EP - 282
JO - Clinics in Chest Medicine
JF - Clinics in Chest Medicine
SN - 0272-5231
IS - 2
ER -