Thyroid stimulating hormone stability in patients prescribed synthetic or desiccated thyroid products: A retrospective study

Rolake Kuye; Catherine Riggs; Jordan King; Rachel Heilmann; Deanna Kurz; Jessica Milchak

doi:10.1370/afm.2545

Thyroid stimulating hormone stability in patients prescribed synthetic or desiccated thyroid products: A retrospective study

Rolake Kuye, Catherine Riggs, Jordan King, Rachel Heilmann, Deanna Kurz, Jessica Milchak

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Abstract

The purpose of this retrospective matched-cohort study was to evaluate the stability of thyroid stimulating hormone (TSH) in patients using synthetic compared with desiccated thyroid products. Patients using a thyroid product for the treatment of hypothyroidism were matched 1:1 on age, sex, race/ethnicity, and had a follow-up period of 3 years after the index date. The primary outcome was percent of in-range TSH values. Over 3 years, TSH values in both groups were in-range 79% of the time (P = 0.905). Our results showed no difference in longitudinal TSH stability between desiccated thyroid products and synthetic levothyroxine.

Original language	English
Pages (from-to)	452-454
Number of pages	3
Journal	Annals of family medicine
Volume	18
Issue number	5
DOIs	https://doi.org/10.1370/afm.2545
State	Published - 2020

Keywords

Desiccated thyroid
Hypothyroidism
Levothyroxine
Stability
Thyroid stimulating hormone (TSH)
Thyrotropin, thyroxine, thyroid (USP)

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abstract = "The purpose of this retrospective matched-cohort study was to evaluate the stability of thyroid stimulating hormone (TSH) in patients using synthetic compared with desiccated thyroid products. Patients using a thyroid product for the treatment of hypothyroidism were matched 1:1 on age, sex, race/ethnicity, and had a follow-up period of 3 years after the index date. The primary outcome was percent of in-range TSH values. Over 3 years, TSH values in both groups were in-range 79% of the time (P = 0.905). Our results showed no difference in longitudinal TSH stability between desiccated thyroid products and synthetic levothyroxine.",

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AU - Riggs, Catherine

AU - King, Jordan

AU - Heilmann, Rachel

AU - Kurz, Deanna

AU - Milchak, Jessica

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Thyroid stimulating hormone stability in patients prescribed synthetic or desiccated thyroid products: A retrospective study

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