The therapeutic promise of positive allosteric modulation of nicotinic receptors

Keyphrases

• Therapeutic Promises 100%
• Nicotinic Acetylcholine Receptor (nAChR) 100%
• Positive Allosteric Modulation 100%
• Positive Allosteric Modulator 57%
• Brain Regions 28%
• Cholinergic Tone 28%
• Therapeutic Applications 28%
• Central Nervous System 14%
• Hippocampus 14%
• Neuronal Damage 14%
• Cognitive Impairment 14%
• Neuropathology 14%
• Anti-inflammatory Effect 14%
• Choline 14%
• Cortex 14%
• Cholinergic Hypofunction 14%
• Existing Trends 14%
• Rational Basis 14%
• Selective Agonist 14%
• Disease-related 14%
• Nicotinic Agonists 14%
• Neurological Impairment 14%
• Attention Impairment 14%
• Injury Levels 14%
• Increased Safety 14%
• Injury Type 14%
• Orthosteric 14%
• Penumbra 14%
• Non-neuronal Tissues 14%
• Analgesic 14%
• Differential Effectiveness 14%
• Activation Level 14%
• Cognitive Performance 14%
• Cholinergic Neurotransmission 14%
• Posttraumatic Stress 14%
• Efficacy Safety 14%
• Orthosteric Agonist 14%

Neuroscience

• Nicotinic Receptor 100%
• Positive Allosteric Modulator 80%
• Cholinergic 60%
• Nicotinic Acetylcholine Receptor 40%
• Agonist 40%
• Nicotinic Agonist 40%
• Brain Region 40%
• Central Nervous System 20%
• Anti-Inflammatory 20%
• Hippocampus 20%
• Cognitive Disorders 20%
• Choline 20%
• Cholinergic Transmission 20%

Pharmacology, Toxicology and Pharmaceutical Science

• Nicotinic Receptor 100%
• Positive Allosteric Modulator 57%
• Cholinergic Receptor Stimulating Agent 57%
• Nicotinic Agent 28%
• Cognitive Defect 14%
• Choline 14%
• Analgesic Agent 14%
• Antiinflammatory Activity 14%
• Therapeutic Use 14%
• Diseases 14%