The redistribution of power

Neurocardiac signaling, alcohol and gender

Marsha E. Bates, Jennifer F. Buckman, Evgeny G. Vaschillo, Vladimir A. Fonoberov, Maria Fonoberova, Bronya Vaschillo, Eun-Young Mun, Adriana Mezić, Igor Mezić

Research output: Contribution to journalArticleResearchpeer-review

9 Citations (Scopus)

Abstract

Human adaptability involves interconnected biological and psychological control processes that determine how successful we are in meeting internal and environmental challenges. Heart rate variability (HRV), the variability in consecutive R-wave to R-wave intervals (RRI) of the electrocardiogram, captures synergy between the brain and cardiovascular control systems that modulate adaptive responding. Here we introduce a qualitatively new dimension of adaptive change in HRV quantified as a redistribution of spectral power by applying the Wasserstein distance with exponent 1 metric (W 1) to RRI spectral data. We further derived a new index, D, to specify the direction of spectral redistribution and clarify physiological interpretation. We examined gender differences in real time RRI spectral power response to alcohol, placebo and visual cue challenges. Adaptive changes were observed as changes in power of the various spectral frequency bands (i.e., standard frequency domain HRV indices) and, during both placebo and alcohol intoxication challenges, as changes in the structure (shape) of the RRI spectrum, with a redistribution towards lower frequency oscillations. The overall conclusions from the present study are that the RRI spectrum is capable of a fluid and highly flexible response, even when oscillations (and thus activity at the sinoatrial node) are pharmacologically suppressed, and that low frequency oscillations serve a crucial but less studied role in physical and mental health.

Original languageEnglish
Article numbere28281
JournalPLoS ONE
Volume6
Issue number12
DOIs
StatePublished - 2 Dec 2011

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alcohols
Heart Rate
Alcohols
oscillation
heart rate
gender
Placebos
placebos
Alcoholic Intoxication
Sinoatrial Node
Cardiovascular System
mental health
Cues
electrocardiography
Mental Health
Electrocardiography
process control
gender differences
spectral analysis
Psychology

Cite this

Bates, M. E., Buckman, J. F., Vaschillo, E. G., Fonoberov, V. A., Fonoberova, M., Vaschillo, B., ... Mezić, I. (2011). The redistribution of power: Neurocardiac signaling, alcohol and gender. PLoS ONE, 6(12), [e28281]. https://doi.org/10.1371/journal.pone.0028281
Bates, Marsha E. ; Buckman, Jennifer F. ; Vaschillo, Evgeny G. ; Fonoberov, Vladimir A. ; Fonoberova, Maria ; Vaschillo, Bronya ; Mun, Eun-Young ; Mezić, Adriana ; Mezić, Igor. / The redistribution of power : Neurocardiac signaling, alcohol and gender. In: PLoS ONE. 2011 ; Vol. 6, No. 12.
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Bates, ME, Buckman, JF, Vaschillo, EG, Fonoberov, VA, Fonoberova, M, Vaschillo, B, Mun, E-Y, Mezić, A & Mezić, I 2011, 'The redistribution of power: Neurocardiac signaling, alcohol and gender', PLoS ONE, vol. 6, no. 12, e28281. https://doi.org/10.1371/journal.pone.0028281

The redistribution of power : Neurocardiac signaling, alcohol and gender. / Bates, Marsha E.; Buckman, Jennifer F.; Vaschillo, Evgeny G.; Fonoberov, Vladimir A.; Fonoberova, Maria; Vaschillo, Bronya; Mun, Eun-Young; Mezić, Adriana; Mezić, Igor.

In: PLoS ONE, Vol. 6, No. 12, e28281, 02.12.2011.

Research output: Contribution to journalArticleResearchpeer-review

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Bates ME, Buckman JF, Vaschillo EG, Fonoberov VA, Fonoberova M, Vaschillo B et al. The redistribution of power: Neurocardiac signaling, alcohol and gender. PLoS ONE. 2011 Dec 2;6(12). e28281. https://doi.org/10.1371/journal.pone.0028281