Abstract
This study represents the first attempt to simultaneously explore the comprehensive relationship between acupuncture, circulating endorphins, and relief of both the pain and psychiatric symptoms of the chronic pain syndrome in a well-defined patient group. Our results indicate that acupuncture is effective in relieving both the pain and the psychiatric symptoms of this illness, and that its effectiveness is correlated with increases in plasma met-enkephalin immunoreactivity. It should also be noted that we cannot infer that the clinical and biochemical results seen in our study are specific for acupuncture. Our results could also be explained by the placebo effect, which has been proposed to involve endorphins (56,57). Studies to test this hypothesis are currently under way in our laboratories.
| Original language | English |
|---|---|
| Pages (from-to) | 139-145 |
| Number of pages | 7 |
| Journal | Clinical Journal of Pain |
| Volume | 1 |
| Issue number | 3 |
| State | Published - 1 Jan 1985 |
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The psychobiology of opioid peptides in acupuncture treatment of chronic pain. / Khatami, M.; Kiser, S.; Gatchel, Robert Joseph.
In: Clinical Journal of Pain, Vol. 1, No. 3, 01.01.1985, p. 139-145.Research output: Contribution to journal › Article
TY - JOUR
T1 - The psychobiology of opioid peptides in acupuncture treatment of chronic pain
AU - Khatami, M.
AU - Kiser, S.
AU - Gatchel, Robert Joseph
PY - 1985/1/1
Y1 - 1985/1/1
N2 - This study represents the first attempt to simultaneously explore the comprehensive relationship between acupuncture, circulating endorphins, and relief of both the pain and psychiatric symptoms of the chronic pain syndrome in a well-defined patient group. Our results indicate that acupuncture is effective in relieving both the pain and the psychiatric symptoms of this illness, and that its effectiveness is correlated with increases in plasma met-enkephalin immunoreactivity. It should also be noted that we cannot infer that the clinical and biochemical results seen in our study are specific for acupuncture. Our results could also be explained by the placebo effect, which has been proposed to involve endorphins (56,57). Studies to test this hypothesis are currently under way in our laboratories.
AB - This study represents the first attempt to simultaneously explore the comprehensive relationship between acupuncture, circulating endorphins, and relief of both the pain and psychiatric symptoms of the chronic pain syndrome in a well-defined patient group. Our results indicate that acupuncture is effective in relieving both the pain and the psychiatric symptoms of this illness, and that its effectiveness is correlated with increases in plasma met-enkephalin immunoreactivity. It should also be noted that we cannot infer that the clinical and biochemical results seen in our study are specific for acupuncture. Our results could also be explained by the placebo effect, which has been proposed to involve endorphins (56,57). Studies to test this hypothesis are currently under way in our laboratories.
UR - http://www.scopus.com/inward/record.url?scp=0022377099&partnerID=8YFLogxK
M3 - Article
AN - SCOPUS:0022377099
VL - 1
SP - 139
EP - 145
JO - Clinical Journal of Pain
JF - Clinical Journal of Pain
SN - 0749-8047
IS - 3
ER -