The Link between Potassium and Mild Cognitive Impairment in Mexican-Americans

Raul M. Vintimilla; Stephanie E. Large; Adriana Gamboa; Geoffrey D. Rohlfing; Judith R. O'Jile; James R. Hall; Sid E. O'Bryant; Leigh A. Johnson

doi:10.1159/000488483

The Link between Potassium and Mild Cognitive Impairment in Mexican-Americans

Raul M. Vintimilla, Stephanie E. Large, Adriana Gamboa, Geoffrey D. Rohlfing, Judith R. O'Jile, James R. Hall, Sid E. O'Bryant, Leigh A. Johnson

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8 Scopus citations

Abstract

Background: Recent evidence suggests that increasing dietary intake of minerals reduces the risk of dementia. This study aimed to examine the relationship between potassium and diagnosis of mild cognitive impairment (MCI) in a sample of older Mexican-Americans from rural and urban populations. Methods: The sample was formed of a total of 139 participants with MCI and 371 normal controls from two independent cohorts: a rural cohort (Facing Rural Obstacles to Healthcare Now through Intervention, Education and Research [Project FRONTIER]) and an urban cohort (the Health and Aging Brain among Latino Elders [HABLE] study). Serum electrolytes examined were sodium and potassium. Age and education were entered in the model as covariates. Results: Across both cohorts, the Project FRONTIER (OR = 3.1; p = 0.01) and the HABLE Project (OR = 2.0; p = 0.04), the results indicated that serum potassium levels significantly increased the risk of diagnosis of MCI. Conclusion: Our finding suggested a link between serum potassium levels and a diagnosis of MCI in Mexican-Americans. The results of this study support a previous research which has suggested that the risk factors for MCI may vary by ethnicity.

Original language	English
Pages (from-to)	151-157
Number of pages	7
Journal	Dementia and Geriatric Cognitive Disorders Extra
Volume	8
Issue number	1
DOIs	https://doi.org/10.1159/000488483
State	Published - 1 Jan 2018

Keywords

Cognition
Electrolytes
Hispanic population
Memory

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10.1159/000488483

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@article{e3f2ad3369e744ffa5ebb1209dc0054d,

title = "The Link between Potassium and Mild Cognitive Impairment in Mexican-Americans",

abstract = "Background: Recent evidence suggests that increasing dietary intake of minerals reduces the risk of dementia. This study aimed to examine the relationship between potassium and diagnosis of mild cognitive impairment (MCI) in a sample of older Mexican-Americans from rural and urban populations. Methods: The sample was formed of a total of 139 participants with MCI and 371 normal controls from two independent cohorts: a rural cohort (Facing Rural Obstacles to Healthcare Now through Intervention, Education and Research [Project FRONTIER]) and an urban cohort (the Health and Aging Brain among Latino Elders [HABLE] study). Serum electrolytes examined were sodium and potassium. Age and education were entered in the model as covariates. Results: Across both cohorts, the Project FRONTIER (OR = 3.1; p = 0.01) and the HABLE Project (OR = 2.0; p = 0.04), the results indicated that serum potassium levels significantly increased the risk of diagnosis of MCI. Conclusion: Our finding suggested a link between serum potassium levels and a diagnosis of MCI in Mexican-Americans. The results of this study support a previous research which has suggested that the risk factors for MCI may vary by ethnicity.",

keywords = "Cognition, Electrolytes, Hispanic population, Memory",

author = "Vintimilla, {Raul M.} and Large, {Stephanie E.} and Adriana Gamboa and Rohlfing, {Geoffrey D.} and O'Jile, {Judith R.} and Hall, {James R.} and O'Bryant, {Sid E.} and Johnson, {Leigh A.}",

note = "Funding Information: Research reported in this publication was supported by the National Institute on Aging of the National Institutes of Health under Award Number R 眃砀AG 爃眃瘃爃礃甁 The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health. This research was also funded, in part, by the Environmental Protection Agency (RD 稃甃瘃礃笃瘂I, the Hogg Foundation for Mental Health (JRG-爃瘃爀 and JRG-猃瘃笂I, and The Pfeiffer foundation. The research team also thanks the local Fort Worth community and participants of the Health and Aging Brain Study. The funding bodies had no role in the study design, data collection, analyses, or preparation of the paper. Publisher Copyright: {\textcopyright} 2018 The Author(s) Published by S. Karger AG, Basel.",

year = "2018",

month = jan,

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doi = "10.1159/000488483",

language = "English",

volume = "8",

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T1 - The Link between Potassium and Mild Cognitive Impairment in Mexican-Americans

AU - Vintimilla, Raul M.

AU - Large, Stephanie E.

AU - Gamboa, Adriana

AU - Rohlfing, Geoffrey D.

AU - O'Jile, Judith R.

AU - Hall, James R.

AU - O'Bryant, Sid E.

AU - Johnson, Leigh A.

N1 - Funding Information: Research reported in this publication was supported by the National Institute on Aging of the National Institutes of Health under Award Number R 眃砀AG 爃眃瘃爃礃甁 The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health. This research was also funded, in part, by the Environmental Protection Agency (RD 稃甃瘃礃笃瘂I, the Hogg Foundation for Mental Health (JRG-爃瘃爀 and JRG-猃瘃笂I, and The Pfeiffer foundation. The research team also thanks the local Fort Worth community and participants of the Health and Aging Brain Study. The funding bodies had no role in the study design, data collection, analyses, or preparation of the paper. Publisher Copyright: © 2018 The Author(s) Published by S. Karger AG, Basel.

PY - 2018/1/1

Y1 - 2018/1/1

N2 - Background: Recent evidence suggests that increasing dietary intake of minerals reduces the risk of dementia. This study aimed to examine the relationship between potassium and diagnosis of mild cognitive impairment (MCI) in a sample of older Mexican-Americans from rural and urban populations. Methods: The sample was formed of a total of 139 participants with MCI and 371 normal controls from two independent cohorts: a rural cohort (Facing Rural Obstacles to Healthcare Now through Intervention, Education and Research [Project FRONTIER]) and an urban cohort (the Health and Aging Brain among Latino Elders [HABLE] study). Serum electrolytes examined were sodium and potassium. Age and education were entered in the model as covariates. Results: Across both cohorts, the Project FRONTIER (OR = 3.1; p = 0.01) and the HABLE Project (OR = 2.0; p = 0.04), the results indicated that serum potassium levels significantly increased the risk of diagnosis of MCI. Conclusion: Our finding suggested a link between serum potassium levels and a diagnosis of MCI in Mexican-Americans. The results of this study support a previous research which has suggested that the risk factors for MCI may vary by ethnicity.

AB - Background: Recent evidence suggests that increasing dietary intake of minerals reduces the risk of dementia. This study aimed to examine the relationship between potassium and diagnosis of mild cognitive impairment (MCI) in a sample of older Mexican-Americans from rural and urban populations. Methods: The sample was formed of a total of 139 participants with MCI and 371 normal controls from two independent cohorts: a rural cohort (Facing Rural Obstacles to Healthcare Now through Intervention, Education and Research [Project FRONTIER]) and an urban cohort (the Health and Aging Brain among Latino Elders [HABLE] study). Serum electrolytes examined were sodium and potassium. Age and education were entered in the model as covariates. Results: Across both cohorts, the Project FRONTIER (OR = 3.1; p = 0.01) and the HABLE Project (OR = 2.0; p = 0.04), the results indicated that serum potassium levels significantly increased the risk of diagnosis of MCI. Conclusion: Our finding suggested a link between serum potassium levels and a diagnosis of MCI in Mexican-Americans. The results of this study support a previous research which has suggested that the risk factors for MCI may vary by ethnicity.

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KW - Electrolytes

KW - Hispanic population

KW - Memory

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DO - 10.1159/000488483

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AN - SCOPUS:85046040841

SN - 1664-5464

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EP - 157

JO - Dementia and Geriatric Cognitive Disorders Extra

JF - Dementia and Geriatric Cognitive Disorders Extra

IS - 1

ER -

The Link between Potassium and Mild Cognitive Impairment in Mexican-Americans

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