The influence of co-morbidities on prescribing pharmacotherapy for insomnia: Evidence from US national outpatient data 1995-2004

Manjiri D. Pawaskar, Vijay N. Joish, Fabian T. Camacho, Rafia S. Rasu, Rajesh Balkrishnan

Research output: Contribution to journalArticlepeer-review

9 Scopus citations

Abstract

Objective: Patients with insomnia are likely to have other co-morbidities that could affect pharmacotherapeutic choices. This study examined the prevalence and impact of co-morbidities on the pharmacological treatment of insomnia. Study design: A retrospective data analysis of the National Ambulatory Medical Care Survey from 1995 to 2004, comprising patients with a diagnosis of insomnia, was conducted. Multivariate logistic regression models were used to predict the impact of co-morbidities on pharmacotherapy for insomnia. Results: A total of 5,487 unweighted patient visits with insomnia were identified, representing 161.4 million patients in the US. Approximately 38% of these patients had at least one co-morbid condition. Patients with mental co-morbidities, especially anxiety, had decreased likelihood of receiving pharmacotherapy for insomnia. Conclusions: Mental co-morbidities such as episodic mood disorder, anxiety and depression are prevalent in patients with insomnia. However, many co-morbid patients do not receive pharmacological therapy specific for insomnia.

Original languageEnglish
Pages (from-to)41-56
Number of pages16
JournalJournal of Medical Economics
Volume11
Issue number1
DOIs
StatePublished - 2008

Keywords

  • Benzodiazepine
  • Co-morbidity
  • Insomnia
  • Non-benzodiazepine
  • Pharmacotherapy

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