The incidence of hepatitis e virus infection in the general population of the USA

M. F. Faramawi, E. Johnson, S. Chen, P. R. Pannala

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37 Scopus citations


Hepatitis E virus (HEV) infection is as an emerging disease of global importance because it is one of the major causes of acute hepatitis worldwide. There are few reports on the incidence of HEV in the USA. For better assessing the burden of primary HEV infection as well as understanding the epidemiology of HEV in the US population this analysis was conducted to estimate the force of infection of HEV in the USA. HEV force of infection in the general US population was calculated using catalytic models as cumulative markers of past infection from HEV seroprevalence data from the NHANES Survey. In the US population the force of infection was seven infections per 1000 susceptible persons per year. This study shows that in the USA HEV can be acquired locally and from developing countries. HEV is circulating more frequently in the non-Hispanic White racial/ethnic group and those who consume fish more frequently.

Original languageEnglish
Pages (from-to)1145-1150
Number of pages6
JournalEpidemiology and Infection
Issue number8
StatePublished - Aug 2011


  • Epidemiology
  • USA
  • hepatitis E virus
  • nutritional surveys


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