Abstract
Shigella flexneri rods play an important role in human intestinal infections. In the presented studies we have shown that O-acetyl and glucose residues, substituted in main GalNAc-Rha chains of lipopolysaccharide (LPS) are important for the bactericidal effect of human serum. By dot-blot, immunoblotting and ELISA with immobilized LPS we have shown correlation of C3 fragments deposition and serum resistance. LPSs isolated from a serum-sensitive strain deposited more C3 fragments than LPSs from serum-resistant Shigella flexneri strains.
Original language | English |
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Pages (from-to) | 45-52 |
Number of pages | 8 |
Journal | Acta Microbiologica Polonica |
Volume | 52 |
Issue number | 1 |
State | Published - 2003 |
Keywords
- C3 fragments
- Complement
- Lipopolysacharide
- Shigella flexneri