The effects of inbreeding on DNA profile frequency estimates using PCR-based loci

Research output: Contribution to journalArticle

9 Scopus citations

Abstract

Estimates of inbreeding were determined using Wright's FST for loci used for PCR-based forensic analyses. The populations analyzed were African Americans, Caucasians, Hispanics, and Orientals. In most cases the FST values at each locus were less than 0.01. The FST values over all loci for African Americans, Caucasians, and Orientals ranged from 0.0015 to 0.0048. No substantial differences were observed for DNA profile frequency estimates when calculated under the assumption of independence or with the incorporation of FST.

Original languageEnglish
Pages (from-to)21-25
Number of pages5
JournalGenetica
Volume96
Issue number1-2
DOIs
Publication statusPublished - 1 Jun 1995

    Fingerprint

Keywords

  • African American
  • Caucasian
  • DNA profile
  • Hardy-Weinberg Expectations
  • Hispanic
  • Oriental
  • PCR
  • inbreeding
  • population substructure

Cite this