The effects of central norepinephrine infusions on drinking behavior induced by angiotensin after 6-hydroxydopamine injections into the anteroventral region of the third ventricle (AV3V)

J. Thomas Cunningham, Alan Kim Johnson

Research output: Contribution to journalArticle

32 Scopus citations

Abstract

Adult male Sprague-Dawley rats were injected with either 6-hydroxydopamine (6-OHDA) or vehicle in the median preoptic nucleus and the organum vasculosum of the lamina terminalis. The subjects were tested for drinking responses to intraventricular angiotensin II (ANG II) or saline during either saline or norepinephrine intraventricular infusions. Rats injected with 6-OHDA into the ventral lamina terminalis initially failed to show drinking responses to ANG II injections. However, norepinephrine infusion in combination with ANG II injection restored the drinking response to ANG II in rats with catecholamine depletions of the lamina terminalis region.

Original languageEnglish
Pages (from-to)112-116
Number of pages5
JournalBrain Research
Volume558
Issue number1
DOIs
StatePublished - 30 Aug 1991

Keywords

  • Catecholamine
  • Dipsogen
  • Median preoptic nucleus
  • Organum vasculosum of the lamina terminalis
  • Thirst

Fingerprint Dive into the research topics of 'The effects of central norepinephrine infusions on drinking behavior induced by angiotensin after 6-hydroxydopamine injections into the anteroventral region of the third ventricle (AV3V)'. Together they form a unique fingerprint.

  • Cite this