The dual effect of PNU-120596 on α₇ nicotinic acetylcholine receptor channels

Keyphrases

• 5-chloro-2 11%
• Acute Brain Slices 11%
• Bicuculline 44%
• CA1 Interneurons 11%
• Channel Data 11%
• Charged Molecules 11%
• Choline 22%
• Choline Chloride 11%
• Desensitization 22%
• Drug Interactions 11%
• Dual Action 11%
• Dual Effect 100%
• Hippocampal CA1 Region 11%
• Inhibitory Interactions 11%
• Misinterpretation 11%
• Nicotinic Acetylcholine Receptor (nAChR) 100%
• Nicotinic Receptors 33%
• Open-channel Block 11%
• Pharmacology 11%
• PNU-120596 100%
• Positive Allosteric Modulator 22%
• Positively Charged 22%
• Receptor Desensitization 11%
• Single Channel 11%
• Transmembrane Voltage 11%
• Urea 11%
• Voltage Dependence 44%
• Voltage-clamp Recording 11%
• Whole-cell Voltage Clamp 11%

Neuroscience

• Agonist 33%
• Bicuculline 100%
• Bicuculline Methochloride 33%
• Brain Slice 33%
• Choline 100%
• Interneuron 33%
• Nicotinic Acetylcholine Receptor 100%
• Nicotinic Receptor 100%
• Positive Allosteric Modulator 66%
• Receptor down Regulation 33%
• Voltage Clamp 33%

Pharmacology, Toxicology and Pharmaceutical Science

• Bicuculline 60%
• Bicuculline Methochloride 20%
• Choline 60%
• Desensitization 60%
• Drug Interaction 20%
• Nicotinic Receptor 100%
• Positive Allosteric Modulator 40%