Abstract
Allele and genotype frequencies for the HLA-130α locus were determined for use in forensic analyses and paternity tests in Finland. The polymerase chain reaction (PCR) and the reverse dot blot format were employed to detect 6 different HLA-DQα alleles. All 6 HLA-DQα alleles were detected among the 112 unrelated individuals with allele frequencies ranging from 5.8% to 32.6%. The distribution of the observed genotypes is in Hardy-Weinberg equilibrium. Additionally, this Finnish population sample is statistically similar to 2 other Caucasian sample populations. The power of discrimination of this system in the Finnish population sample is 0.92, suggesting this method may prove suitable for identification purposes.
Original language | English |
---|---|
Pages (from-to) | 181-184 |
Number of pages | 4 |
Journal | International journal of legal medicine |
Volume | 104 |
Issue number | 4 |
DOIs | |
State | Published - Jul 1991 |
Keywords
- Allele specific oligonucleotides
- Finnish population
- HLADQα
- Polymerase chain reaction (PCR)
- Population genetics