The complement component C4 in black Americans with Type 1 (insulin-dependent) diabetes mellitus

B. Budowle, J. M. Roseman, R. C.P. Go, B. O. Barger, R. T. Acton

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

The complement component C4 variants C4A4, C4B 4 and C4B QO were found to be significantly increased in 64 black patients with Type 1 (insulin-dependent) diabetes compared with 169 black control subjects, yielding relative risks of 3.3, 2.9 and 3.4, respectively. The increased frequencies of C4B 4 and C4B QO in black Type 1 diabetic patients are similar to those found in Caucasoid Type 1 diabetic patients. The data suggest that Type 1 diabetes in black Americans may be partially due to admixture of genes from whites.

Original languageEnglish
Pages (from-to)166-168
Number of pages3
JournalDiabetologia
Volume26
Issue number2
DOIs
StatePublished - 1 Feb 1984

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Complement C4
Type 1 Diabetes Mellitus
Insulin
Genes

Keywords

  • Complement component C4
  • Type 1 diabetes mellitus
  • black Americans

Cite this

Budowle, B. ; Roseman, J. M. ; Go, R. C.P. ; Barger, B. O. ; Acton, R. T. / The complement component C4 in black Americans with Type 1 (insulin-dependent) diabetes mellitus. In: Diabetologia. 1984 ; Vol. 26, No. 2. pp. 166-168.
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The complement component C4 in black Americans with Type 1 (insulin-dependent) diabetes mellitus. / Budowle, B.; Roseman, J. M.; Go, R. C.P.; Barger, B. O.; Acton, R. T.

In: Diabetologia, Vol. 26, No. 2, 01.02.1984, p. 166-168.

Research output: Contribution to journalArticle

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