Abstract
The complement component C4 variants C4A4, C4B 4 and C4B QO were found to be significantly increased in 64 black patients with Type 1 (insulin-dependent) diabetes compared with 169 black control subjects, yielding relative risks of 3.3, 2.9 and 3.4, respectively. The increased frequencies of C4B 4 and C4B QO in black Type 1 diabetic patients are similar to those found in Caucasoid Type 1 diabetic patients. The data suggest that Type 1 diabetes in black Americans may be partially due to admixture of genes from whites.
Original language | English |
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Pages (from-to) | 166-168 |
Number of pages | 3 |
Journal | Diabetologia |
Volume | 26 |
Issue number | 2 |
DOIs | |
State | Published - Feb 1984 |
Keywords
- Complement component C4
- Type 1 diabetes mellitus
- black Americans