The complement component C4 in black Americans with Type 1 (insulin-dependent) diabetes mellitus

B. Budowle; J. M. Roseman; R. C.P. Go; B. O. Barger; R. T. Acton

doi:10.1007/BF00281127

The complement component C4 in black Americans with Type 1 (insulin-dependent) diabetes mellitus

B. Budowle, J. M. Roseman, R. C.P. Go, B. O. Barger, R. T. Acton

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

The complement component C4 variants C4A4, C4B 4 and C4B QO were found to be significantly increased in 64 black patients with Type 1 (insulin-dependent) diabetes compared with 169 black control subjects, yielding relative risks of 3.3, 2.9 and 3.4, respectively. The increased frequencies of C4B 4 and C4B QO in black Type 1 diabetic patients are similar to those found in Caucasoid Type 1 diabetic patients. The data suggest that Type 1 diabetes in black Americans may be partially due to admixture of genes from whites.

Original language	English
Pages (from-to)	166-168
Number of pages	3
Journal	Diabetologia
Volume	26
Issue number	2
DOIs	https://doi.org/10.1007/BF00281127
State	Published - Feb 1984

Keywords

Complement component C4
Type 1 diabetes mellitus
black Americans

Access to Document

10.1007/BF00281127

Cite this

@article{2a9791eee7f7423f99353d690cd8d9c4,

title = "The complement component C4 in black Americans with Type 1 (insulin-dependent) diabetes mellitus",

abstract = "The complement component C4 variants C4A4, C4B 4 and C4B QO were found to be significantly increased in 64 black patients with Type 1 (insulin-dependent) diabetes compared with 169 black control subjects, yielding relative risks of 3.3, 2.9 and 3.4, respectively. The increased frequencies of C4B 4 and C4B QO in black Type 1 diabetic patients are similar to those found in Caucasoid Type 1 diabetic patients. The data suggest that Type 1 diabetes in black Americans may be partially due to admixture of genes from whites.",

keywords = "Complement component C4, Type 1 diabetes mellitus, black Americans",

author = "B. Budowle and Roseman, {J. M.} and Go, {R. C.P.} and Barger, {B. O.} and Acton, {R. T.}",

year = "1984",

month = feb,

doi = "10.1007/BF00281127",

language = "English",

volume = "26",

pages = "166--168",

journal = "Diabetologia",

issn = "0012-186X",

publisher = "Springer Verlag",

number = "2",

}

TY - JOUR

T1 - The complement component C4 in black Americans with Type 1 (insulin-dependent) diabetes mellitus

AU - Budowle, B.

AU - Roseman, J. M.

AU - Go, R. C.P.

AU - Barger, B. O.

AU - Acton, R. T.

PY - 1984/2

Y1 - 1984/2

N2 - The complement component C4 variants C4A4, C4B 4 and C4B QO were found to be significantly increased in 64 black patients with Type 1 (insulin-dependent) diabetes compared with 169 black control subjects, yielding relative risks of 3.3, 2.9 and 3.4, respectively. The increased frequencies of C4B 4 and C4B QO in black Type 1 diabetic patients are similar to those found in Caucasoid Type 1 diabetic patients. The data suggest that Type 1 diabetes in black Americans may be partially due to admixture of genes from whites.

AB - The complement component C4 variants C4A4, C4B 4 and C4B QO were found to be significantly increased in 64 black patients with Type 1 (insulin-dependent) diabetes compared with 169 black control subjects, yielding relative risks of 3.3, 2.9 and 3.4, respectively. The increased frequencies of C4B 4 and C4B QO in black Type 1 diabetic patients are similar to those found in Caucasoid Type 1 diabetic patients. The data suggest that Type 1 diabetes in black Americans may be partially due to admixture of genes from whites.

KW - Complement component C4

KW - Type 1 diabetes mellitus

KW - black Americans

UR - http://www.scopus.com/inward/record.url?scp=0021359665&partnerID=8YFLogxK

U2 - 10.1007/BF00281127

DO - 10.1007/BF00281127

M3 - Article

C2 - 6714536

AN - SCOPUS:0021359665

SN - 0012-186X

VL - 26

SP - 166

EP - 168

JO - Diabetologia

JF - Diabetologia

IS - 2

ER -

The complement component C4 in black Americans with Type 1 (insulin-dependent) diabetes mellitus

Abstract

Keywords

Access to Document

Other files and links

Fingerprint

Cite this