Tension generation by isolated myofibrils

Julian Borejdo; A. Schweitzer

Tension generation by isolated myofibrils

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Abstract

The technique for mechanical dissection of microscopic myofibrilar bundles containing few myofibrils is described. A sensitive electrooptical tension transducer capable of resolving the tension generated by such myofibrilar bundles to within a fraction of a percent is used to study the response of the preparations to low ATP concentrations. The rate of tension development decreased with a decrease in ATP concentration. Below 10^-6 M ATP the myofibrils did not demonstrate any mechanical activity at all. These findings are discussed in terms of the kinetics of the crossbridge cycle.

Original language	English
Pages (from-to)	189-204
Number of pages	16
Journal	Journal of Mechanochemistry and Cell Motility
Volume	4
Issue number	3
State	Published - 1 Dec 1977

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title = "Tension generation by isolated myofibrils",

abstract = "The technique for mechanical dissection of microscopic myofibrilar bundles containing few myofibrils is described. A sensitive electrooptical tension transducer capable of resolving the tension generated by such myofibrilar bundles to within a fraction of a percent is used to study the response of the preparations to low ATP concentrations. The rate of tension development decreased with a decrease in ATP concentration. Below 10-6 M ATP the myofibrils did not demonstrate any mechanical activity at all. These findings are discussed in terms of the kinetics of the crossbridge cycle.",

author = "Julian Borejdo and A. Schweitzer",

year = "1977",

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T1 - Tension generation by isolated myofibrils

AU - Borejdo, Julian

AU - Schweitzer, A.

PY - 1977/12/1

Y1 - 1977/12/1

N2 - The technique for mechanical dissection of microscopic myofibrilar bundles containing few myofibrils is described. A sensitive electrooptical tension transducer capable of resolving the tension generated by such myofibrilar bundles to within a fraction of a percent is used to study the response of the preparations to low ATP concentrations. The rate of tension development decreased with a decrease in ATP concentration. Below 10-6 M ATP the myofibrils did not demonstrate any mechanical activity at all. These findings are discussed in terms of the kinetics of the crossbridge cycle.

AB - The technique for mechanical dissection of microscopic myofibrilar bundles containing few myofibrils is described. A sensitive electrooptical tension transducer capable of resolving the tension generated by such myofibrilar bundles to within a fraction of a percent is used to study the response of the preparations to low ATP concentrations. The rate of tension development decreased with a decrease in ATP concentration. Below 10-6 M ATP the myofibrils did not demonstrate any mechanical activity at all. These findings are discussed in terms of the kinetics of the crossbridge cycle.

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VL - 4

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EP - 204

JO - Journal of Mechanochemistry and Cell Motility

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