Abstract
The technique for mechanical dissection of microscopic myofibrilar bundles containing few myofibrils is described. A sensitive electrooptical tension transducer capable of resolving the tension generated by such myofibrilar bundles to within a fraction of a percent is used to study the response of the preparations to low ATP concentrations. The rate of tension development decreased with a decrease in ATP concentration. Below 10-6 M ATP the myofibrils did not demonstrate any mechanical activity at all. These findings are discussed in terms of the kinetics of the crossbridge cycle.
| Original language | English |
|---|---|
| Pages (from-to) | 189-204 |
| Number of pages | 16 |
| Journal | Journal of Mechanochemistry and Cell Motility |
| Volume | 4 |
| Issue number | 3 |
| State | Published - 1 Dec 1977 |
Fingerprint Dive into the research topics of 'Tension generation by isolated myofibrils'. Together they form a unique fingerprint.
Cite this
Borejdo, J., & Schweitzer, A. (1977). Tension generation by isolated myofibrils. Journal of Mechanochemistry and Cell Motility, 4(3), 189-204.