Synthesis of deuterated dexanabinol, a nonpsychotropic cannabinoid with neuroprotective properties

Emil Pop; Bogumila Rachwal; Stanislaw Rachwal; Jirina Vlasak; Marcus E. Brewster; Laszlo Prokai

doi:10.1002/(SICI)1099-1344(1998100)41:10<885::AID-JLCR139>3.0.CO;2-6

Synthesis of deuterated dexanabinol, a nonpsychotropic cannabinoid with neuroprotective properties

Emil Pop, Bogumila Rachwal, Stanislaw Rachwal, Jirina Vlasak, Marcus E. Brewster, Laszlo Prokai

Institute for Healthy Aging

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Abstract

The deuterium labeled form of dexanabinol, a potential neuroprotective agent, was synthesized by coupling the deuterated 5-(1,1-dimethylheptyl)resorcinol, obtained in a 5-step procedure, with 4-hydroxymyrtenyl pivalate, followed by deprotection.

Original language	English
Pages (from-to)	885-897
Number of pages	13
Journal	Journal of Labelled Compounds and Radiopharmaceuticals
Volume	41
Issue number	10
DOIs	https://doi.org/10.1002/(SICI)1099-1344(1998100)41:10<885::AID-JLCR139>3.0.CO;2-6
State	Published - 1 Oct 1998

Keywords

Dexanabinol
Neuroprotection
Nonpsychotropic cannabinoids

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10.1002/(SICI)1099-1344(1998100)41:10<885::AID-JLCR139>3.0.CO;2-6

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title = "Synthesis of deuterated dexanabinol, a nonpsychotropic cannabinoid with neuroprotective properties",

abstract = "The deuterium labeled form of dexanabinol, a potential neuroprotective agent, was synthesized by coupling the deuterated 5-(1,1-dimethylheptyl)resorcinol, obtained in a 5-step procedure, with 4-hydroxymyrtenyl pivalate, followed by deprotection.",

keywords = "Dexanabinol, Neuroprotection, Nonpsychotropic cannabinoids",

author = "Emil Pop and Bogumila Rachwal and Stanislaw Rachwal and Jirina Vlasak and Brewster, {Marcus E.} and Laszlo Prokai",

year = "1998",

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T1 - Synthesis of deuterated dexanabinol, a nonpsychotropic cannabinoid with neuroprotective properties

AU - Pop, Emil

AU - Rachwal, Bogumila

AU - Rachwal, Stanislaw

AU - Vlasak, Jirina

AU - Brewster, Marcus E.

AU - Prokai, Laszlo

PY - 1998/10/1

Y1 - 1998/10/1

N2 - The deuterium labeled form of dexanabinol, a potential neuroprotective agent, was synthesized by coupling the deuterated 5-(1,1-dimethylheptyl)resorcinol, obtained in a 5-step procedure, with 4-hydroxymyrtenyl pivalate, followed by deprotection.

AB - The deuterium labeled form of dexanabinol, a potential neuroprotective agent, was synthesized by coupling the deuterated 5-(1,1-dimethylheptyl)resorcinol, obtained in a 5-step procedure, with 4-hydroxymyrtenyl pivalate, followed by deprotection.

KW - Dexanabinol

KW - Neuroprotection

KW - Nonpsychotropic cannabinoids

UR - http://www.scopus.com/inward/record.url?scp=0031768706&partnerID=8YFLogxK

U2 - 10.1002/(SICI)1099-1344(1998100)41:10<885::AID-JLCR139>3.0.CO;2-6

DO - 10.1002/(SICI)1099-1344(1998100)41:10<885::AID-JLCR139>3.0.CO;2-6

M3 - Article

AN - SCOPUS:0031768706

SN - 0362-4803

VL - 41

SP - 885

EP - 897

JO - Journal of Labelled Compounds and Radiopharmaceuticals

JF - Journal of Labelled Compounds and Radiopharmaceuticals

IS - 10

ER -

Synthesis of deuterated dexanabinol, a nonpsychotropic cannabinoid with neuroprotective properties

Abstract

Keywords

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