Swiss Caucasian population data for 13 STR loci using AmpFISTR profiler plus and cofiler PCR amplification kits

Christian Gehrig, Manfred Hochmeister, Urs V. Borer, Richard Dirnhofer, Bruce Budowle

Research output: Contribution to journalArticlepeer-review

18 Scopus citations

Abstract

Allele and genotype frequencies for the 13 core STR loci (D3S1358, VWA, FGA, D8S1179, D21S11, D18S51, D5S818, D13S317, D7S820, THO1, TPOX, CSF1PO, and D16S539) were determined in a Swiss Caucasian population sample (n = 206) using two commercially available multiplex PCR kits (AmpFISTR Profiler Plus and AmpFISTR Cofiler) and subsequent electrophoresis on an ABI PRISM CE 310 Genetic Analyzer instrument. All loci meet Hardy-Weinberg expectations. In addition, there is little evidence for association of alleles among the 13 loci. The allelic frequency data can be used in forensic analyses and paternity tests to estimate the frequency of a multiple STR locus DNA profile in the Swiss population.

Original languageEnglish
Pages (from-to)1035-1038
Number of pages4
JournalJournal of Forensic Sciences
Volume44
Issue number5
DOIs
StatePublished - Sep 1999

Keywords

  • CSF1PO
  • Caucasian
  • D13S317
  • D16S539
  • D18S51
  • D21511
  • D5S818
  • D7S820
  • D8S1179
  • DNA typing
  • DS51358
  • FGA
  • Forensic science
  • Hardy-Weinberg equilibrium
  • Polymerase chain reaction
  • Population genetics
  • Short tandem repeats
  • Switzerland
  • THO1
  • TPOX
  • VWA

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