Swiss Caucasian population data for 13 STR loci using AmpFISTR profiler plus and cofiler PCR amplification kits

Christian Gehrig; Manfred Hochmeister; Urs V. Borer; Richard Dirnhofer; Bruce Budowle

doi:10.1520/jfs12036j

Swiss Caucasian population data for 13 STR loci using AmpFISTR profiler plus and cofiler PCR amplification kits

Christian Gehrig, Manfred Hochmeister, Urs V. Borer, Richard Dirnhofer, Bruce Budowle

Research output: Contribution to journal › Article › peer-review

20 Scopus citations

Abstract

Allele and genotype frequencies for the 13 core STR loci (D3S1358, VWA, FGA, D8S1179, D21S11, D18S51, D5S818, D13S317, D7S820, THO1, TPOX, CSF1PO, and D16S539) were determined in a Swiss Caucasian population sample (n = 206) using two commercially available multiplex PCR kits (AmpFISTR Profiler Plus and AmpFISTR Cofiler) and subsequent electrophoresis on an ABI PRISM CE 310 Genetic Analyzer instrument. All loci meet Hardy-Weinberg expectations. In addition, there is little evidence for association of alleles among the 13 loci. The allelic frequency data can be used in forensic analyses and paternity tests to estimate the frequency of a multiple STR locus DNA profile in the Swiss population.

Original language	English
Pages (from-to)	1035-1038
Number of pages	4
Journal	Journal of Forensic Sciences
Volume	44
Issue number	5
DOIs	https://doi.org/10.1520/jfs12036j
State	Published - Sep 1999

Keywords

CSF1PO
Caucasian
D13S317
D16S539
D18S51
D21511
D5S818
D7S820
D8S1179
DNA typing
DS51358
FGA
Forensic science
Hardy-Weinberg equilibrium
Polymerase chain reaction
Population genetics
Short tandem repeats
Switzerland
THO1
TPOX
VWA

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10.1520/jfs12036j

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title = "Swiss Caucasian population data for 13 STR loci using AmpFISTR profiler plus and cofiler PCR amplification kits",

abstract = "Allele and genotype frequencies for the 13 core STR loci (D3S1358, VWA, FGA, D8S1179, D21S11, D18S51, D5S818, D13S317, D7S820, THO1, TPOX, CSF1PO, and D16S539) were determined in a Swiss Caucasian population sample (n = 206) using two commercially available multiplex PCR kits (AmpFISTR Profiler Plus and AmpFISTR Cofiler) and subsequent electrophoresis on an ABI PRISM CE 310 Genetic Analyzer instrument. All loci meet Hardy-Weinberg expectations. In addition, there is little evidence for association of alleles among the 13 loci. The allelic frequency data can be used in forensic analyses and paternity tests to estimate the frequency of a multiple STR locus DNA profile in the Swiss population.",

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author = "Christian Gehrig and Manfred Hochmeister and Borer, {Urs V.} and Richard Dirnhofer and Bruce Budowle",

year = "1999",

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AU - Gehrig, Christian

AU - Hochmeister, Manfred

AU - Borer, Urs V.

AU - Dirnhofer, Richard

AU - Budowle, Bruce

PY - 1999/9

Y1 - 1999/9

N2 - Allele and genotype frequencies for the 13 core STR loci (D3S1358, VWA, FGA, D8S1179, D21S11, D18S51, D5S818, D13S317, D7S820, THO1, TPOX, CSF1PO, and D16S539) were determined in a Swiss Caucasian population sample (n = 206) using two commercially available multiplex PCR kits (AmpFISTR Profiler Plus and AmpFISTR Cofiler) and subsequent electrophoresis on an ABI PRISM CE 310 Genetic Analyzer instrument. All loci meet Hardy-Weinberg expectations. In addition, there is little evidence for association of alleles among the 13 loci. The allelic frequency data can be used in forensic analyses and paternity tests to estimate the frequency of a multiple STR locus DNA profile in the Swiss population.

AB - Allele and genotype frequencies for the 13 core STR loci (D3S1358, VWA, FGA, D8S1179, D21S11, D18S51, D5S818, D13S317, D7S820, THO1, TPOX, CSF1PO, and D16S539) were determined in a Swiss Caucasian population sample (n = 206) using two commercially available multiplex PCR kits (AmpFISTR Profiler Plus and AmpFISTR Cofiler) and subsequent electrophoresis on an ABI PRISM CE 310 Genetic Analyzer instrument. All loci meet Hardy-Weinberg expectations. In addition, there is little evidence for association of alleles among the 13 loci. The allelic frequency data can be used in forensic analyses and paternity tests to estimate the frequency of a multiple STR locus DNA profile in the Swiss population.

KW - CSF1PO

KW - Caucasian

KW - D13S317

KW - D16S539

KW - D18S51

KW - D21511

KW - D5S818

KW - D7S820

KW - D8S1179

KW - DNA typing

KW - DS51358

KW - FGA

KW - Forensic science

KW - Hardy-Weinberg equilibrium

KW - Polymerase chain reaction

KW - Population genetics

KW - Short tandem repeats

KW - Switzerland

KW - THO1

KW - TPOX

KW - VWA

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DO - 10.1520/jfs12036j

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SN - 0022-1198

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SP - 1035

EP - 1038

JO - Journal of forensic sciences

JF - Journal of forensic sciences

IS - 5

ER -

Swiss Caucasian population data for 13 STR loci using AmpFISTR profiler plus and cofiler PCR amplification kits

Abstract

Keywords

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