Susceptibility of enterococci, methicillin-resistant staphylococcus aureus and streptococcus pneumoniae to the glycylcyclines

William Weiss, N. V. Jacobus, P. J. Petersen, Raymond T. Testa

Research output: Contribution to journalArticlepeer-review

24 Scopus citations

Abstract

The in-vitro activities of two glycylcyclines, DMG-MINO and DMG-DMDOT, and several comparative agents were determined against 263 enterococci, 102 methicillin-resistant Staphylococcus aureus and 55 Streptococcus pneumoniae recent clinical isolates. The glycylcyclines and teicoplanin were the most active agents against the enterococcal isolates. All methicillin-resistant S. aureus were susceptible to the glycylcyclines. Only DMG-DMDOT, ciprofloxacin, teicoplanin and vancomycin exhibited comparable activity against penicillin-susceptible, -intermediateand -resistant S. pneumoniae strains.

Original languageEnglish
Pages (from-to)225-230
Number of pages6
JournalJournal of Antimicrobial Chemotherapy
Volume36
Issue number1
DOIs
StatePublished - 1 Jul 1995

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