Keyphrases
Small Molecule Inhibitors
100%
Potassium Channel
100%
Structure-activity Relationship
100%
Chemotype
100%
Relationship Research
100%
Xanthine
100%
Epilepsy of Infancy with Migrating Focal Seizures (EIMFS)
100%
Tool Compound
50%
Ion Channels
50%
Clinically Significant
50%
Gain-of-function mutation
50%
Developmental Disorders
50%
Potential Therapeutics
50%
Whole Cell
50%
IC50 Value
50%
High-throughput Screening
50%
Sodium-activated Potassium Channels
50%
Potent Inhibitor
50%
Childhood Epilepsy
50%
KCNT1 Gene
50%
Automated Patch Clamp
50%
New Analogs
50%
In Vitro Tools
50%
Hit Optimization
50%
Patch Clamp Assay
50%
Epilepsy Treatment
50%
Epileptic Encephalopathy
50%
Developmental Encephalopathy
50%
HERG
50%
Epilepsy Syndrome
50%
Biochemistry, Genetics and Molecular Biology
Small Molecule
100%
Infancy
100%
Potassium Channel
100%
Whole Cell
50%
Gain of Function Mutation
50%
IC50
50%
KCNT1
50%
Automated Patch Clamp
50%
Ion Channel
50%
Neuroscience
Potassium Channel
100%
Xanthine
100%
In Vitro
50%
Ion Channel
50%
Patch Clamp
50%
Gain of Function Mutation
50%
KCNT1
50%
Treatment of Epilepsy
50%
Pediatric Epilepsy
50%
Brain Disease
50%
Pharmacology, Toxicology and Pharmaceutical Science
Potassium Channel
100%
Focal Epilepsy
100%
Xanthine
100%
Ion Channel
50%
IC50
50%
Developmental Disorder
50%
Brain Disease
50%
Benign Childhood Epilepsy
50%
Chemistry
K
100%
Xanthine
100%
Developmental
100%
Sodium
50%
IC50
50%