Structural determinants stabilizing the axial channel of ClpP for substrate translocation

Keyphrases

• Acyldepsipeptide 60%
• Amino Acid Substitution 20%
• Antibiotics 20%
• ATP Synthase 20%
• Axial Channel 100%
• Bacillus Subtilis (B. subtilis) 20%
• ClpA 20%
• ClpAP 20%
• ClpP 100%
• ClpX 20%
• ClpXP 20%
• Escherichia 20%
• Gating Mechanism 20%
• Gram-negative Bacteria 20%
• Gram-positive 20%
• Hairpin Loop 20%
• Hydrophobic Cluster 20%
• Hydrophobic Pocket 20%
• Mechanistic Insight 20%
• N-terminal Region 20%
• Open Conformation 20%
• Protease 40%
• Protein Substrate 40%
• Structural Requirements 20%
• Substrate Translocation 100%
• Tetradecamer 20%
• Translocated 40%

Biochemistry, Genetics and Molecular Biology

• Amino Acid Substitution 50%
• Conformation 50%
• Gram Negative Bacterium 50%
• N-Terminus 50%
• Protease 100%