Statistical analysis of an Australian population for the loci Gc, HLA-DQA1, D1S80 and HUMTH01

Stephen Gutowski, Bruce Budowle, Jeanette Auer, Roland van Oorschot

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8 Scopus citations

Abstract

Gc phenotyping by immunoblotting is used in the State of Victoria as a rapid screening technique for blood and occasionally, semen evidence. Where no exclusion is obtained samples are further typed with the PCR-based DNA systems HLA-DQA1, D1S80 and HUMTH01. Victorian databases have been generated for these loci. All loci meet Hardy-Weinberg expectations and there is no detectable association between the four loci. The multiplication rule can, therefore, be applied to obtain an appropriate weighting of inclusionary evidence for use in criminal investigations and court proceedings.

Original languageEnglish
Pages (from-to)1-6
Number of pages6
JournalForensic Science International
Volume76
Issue number1
DOIs
StatePublished - 30 Nov 1995

Keywords

  • Australia
  • D1S80
  • Gc
  • HLA-DQA1
  • HUMTH01
  • Hardy-Weinberg equilibrium
  • Linkage equilibrium
  • PCR
  • Population databases

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