Statistical analysis of an Australian population for the loci Gc, HLA-DQA1, D1S80 and HUMTH01

Stephen Gutowski; Bruce Budowle; Jeanette Auer; Roland van Oorschot

doi:10.1016/0379-0738(95)01795-X

Statistical analysis of an Australian population for the loci Gc, HLA-DQA1, D1S80 and HUMTH01

Stephen Gutowski, Bruce Budowle, Jeanette Auer, Roland van Oorschot

Research output: Contribution to journal › Article › peer-review

Abstract

Gc phenotyping by immunoblotting is used in the State of Victoria as a rapid screening technique for blood and occasionally, semen evidence. Where no exclusion is obtained samples are further typed with the PCR-based DNA systems HLA-DQA1, D1S80 and HUMTH01. Victorian databases have been generated for these loci. All loci meet Hardy-Weinberg expectations and there is no detectable association between the four loci. The multiplication rule can, therefore, be applied to obtain an appropriate weighting of inclusionary evidence for use in criminal investigations and court proceedings.

Original language	English
Pages (from-to)	1-6
Number of pages	6
Journal	Forensic Science International
Volume	76
Issue number	1
DOIs	https://doi.org/10.1016/0379-0738(95)01795-X
State	Published - 30 Nov 1995

Keywords

Australia
D1S80
Gc
HLA-DQA1
HUMTH01
Hardy-Weinberg equilibrium
Linkage equilibrium
PCR
Population databases

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title = "Statistical analysis of an Australian population for the loci Gc, HLA-DQA1, D1S80 and HUMTH01",

abstract = "Gc phenotyping by immunoblotting is used in the State of Victoria as a rapid screening technique for blood and occasionally, semen evidence. Where no exclusion is obtained samples are further typed with the PCR-based DNA systems HLA-DQA1, D1S80 and HUMTH01. Victorian databases have been generated for these loci. All loci meet Hardy-Weinberg expectations and there is no detectable association between the four loci. The multiplication rule can, therefore, be applied to obtain an appropriate weighting of inclusionary evidence for use in criminal investigations and court proceedings.",

keywords = "Australia, D1S80, Gc, HLA-DQA1, HUMTH01, Hardy-Weinberg equilibrium, Linkage equilibrium, PCR, Population databases",

author = "Stephen Gutowski and Bruce Budowle and Jeanette Auer and {van Oorschot}, Roland",

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AU - Gutowski, Stephen

AU - Budowle, Bruce

AU - Auer, Jeanette

AU - van Oorschot, Roland

PY - 1995/11/30

Y1 - 1995/11/30

N2 - Gc phenotyping by immunoblotting is used in the State of Victoria as a rapid screening technique for blood and occasionally, semen evidence. Where no exclusion is obtained samples are further typed with the PCR-based DNA systems HLA-DQA1, D1S80 and HUMTH01. Victorian databases have been generated for these loci. All loci meet Hardy-Weinberg expectations and there is no detectable association between the four loci. The multiplication rule can, therefore, be applied to obtain an appropriate weighting of inclusionary evidence for use in criminal investigations and court proceedings.

AB - Gc phenotyping by immunoblotting is used in the State of Victoria as a rapid screening technique for blood and occasionally, semen evidence. Where no exclusion is obtained samples are further typed with the PCR-based DNA systems HLA-DQA1, D1S80 and HUMTH01. Victorian databases have been generated for these loci. All loci meet Hardy-Weinberg expectations and there is no detectable association between the four loci. The multiplication rule can, therefore, be applied to obtain an appropriate weighting of inclusionary evidence for use in criminal investigations and court proceedings.

KW - Australia

KW - D1S80

KW - Gc

KW - HLA-DQA1

KW - HUMTH01

KW - Hardy-Weinberg equilibrium

KW - Linkage equilibrium

KW - PCR

KW - Population databases

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AN - SCOPUS:0029561374

SN - 0379-0738

VL - 76

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JO - Forensic Science International

JF - Forensic Science International

IS - 1

ER -

Statistical analysis of an Australian population for the loci Gc, HLA-DQA1, D1S80 and HUMTH01

Abstract

Keywords

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