TY - JOUR
T1 - Spectroscopic properties of curcumin
T2 - Orientation of transition moments
AU - Mukerjee, Anindita
AU - Sørensen, Thomas J.
AU - Ranjan, Amalendu Prakash
AU - Raut, Sangram Limbaji
AU - Gryczynski, Ignacy
AU - Vishwanatha, Jamboor K.
AU - Gryczynski, Zygmunt
PY - 2010/10/7
Y1 - 2010/10/7
N2 - Curcumin, a naturally occurring yellow-orange pigment with potent antioxidant and antitumor properties, has been attracting researchers from a wide range of fields including chemistry, spectroscopy, biology, and medicine. Ultrafast excited-state processes such as solvation and excited-state intramolecular hydrogen atom transfer (ESIHT) make curcumin an attractive agent for photodynamic therapy. In this report we present studies of linear dichroism and fluorescence anisotropy in oriented and isotropic media. The results show transition moments (long wavelength absorption and emission) oriented along the long molecular axis. Comparison of linear dichroism and excitation anisotropy in oriented and isotropic media suggests that excited-state intramolecular hydrogen atom transfer is probably associated with intramolecular conformational changes that can be constrained in highly stretched poly(vinyl alcohol) (PVA) film.
AB - Curcumin, a naturally occurring yellow-orange pigment with potent antioxidant and antitumor properties, has been attracting researchers from a wide range of fields including chemistry, spectroscopy, biology, and medicine. Ultrafast excited-state processes such as solvation and excited-state intramolecular hydrogen atom transfer (ESIHT) make curcumin an attractive agent for photodynamic therapy. In this report we present studies of linear dichroism and fluorescence anisotropy in oriented and isotropic media. The results show transition moments (long wavelength absorption and emission) oriented along the long molecular axis. Comparison of linear dichroism and excitation anisotropy in oriented and isotropic media suggests that excited-state intramolecular hydrogen atom transfer is probably associated with intramolecular conformational changes that can be constrained in highly stretched poly(vinyl alcohol) (PVA) film.
UR - http://www.scopus.com/inward/record.url?scp=77957292921&partnerID=8YFLogxK
U2 - 10.1021/jp104075f
DO - 10.1021/jp104075f
M3 - Article
C2 - 20839868
AN - SCOPUS:77957292921
SN - 1520-6106
VL - 114
SP - 12679
EP - 12684
JO - Journal of Physical Chemistry B
JF - Journal of Physical Chemistry B
IS - 39
ER -