Solvatochromic dye LDS 798 as microviscosity and pH probe

Hung Doan, Marlius Castillo, Micheline Bejjani, Zhangatay Nurekeyev, Sergei V. Dzyuba, Ignacy Gryczynski, Zygmunt Gryczynski, Sangram Limbaji Raut

Research output: Contribution to journalArticleResearchpeer-review

4 Citations (Scopus)

Abstract

Styryl dyes, specifically LDS group dyes, are known solvatochromic and electrochromic probes for monitoring mitochondrial potential in cellular environments. However, the ability of these dyes to respond to fluctuations in viscosity, pH and temperature has not been established. In this study, we demonstrated that LDS 798 (also known as Styryl-11) can sense environmental viscosity (via fluorescence lifetime changes) as well as pH changes (ratiometric intensity change) in the absence of polarity variations. Polarity changes can be probed by spectral changes using LDS 798. Therefore, all properties of the media should be considered, when these types of dyes are used as electrochromic/solvatochromic sensors in cellular environments.

Original languageEnglish
Pages (from-to)29934-29939
Number of pages6
JournalPhysical Chemistry Chemical Physics
Volume19
Issue number44
DOIs
StatePublished - 1 Jan 2017

Fingerprint

Coloring Agents
dyes
probes
polarity
Viscosity
viscosity
Fluorescence
life (durability)
fluorescence
1-ethyl-4-(4-(p-dimethylaminophenyl)-1,3-butadienyl)quinolinium
Monitoring
sensors
Sensors
Temperature
temperature

Cite this

Doan, Hung ; Castillo, Marlius ; Bejjani, Micheline ; Nurekeyev, Zhangatay ; Dzyuba, Sergei V. ; Gryczynski, Ignacy ; Gryczynski, Zygmunt ; Raut, Sangram Limbaji. / Solvatochromic dye LDS 798 as microviscosity and pH probe. In: Physical Chemistry Chemical Physics. 2017 ; Vol. 19, No. 44. pp. 29934-29939.
@article{4a66160fde684f53831ff59e176f5a5f,
title = "Solvatochromic dye LDS 798 as microviscosity and pH probe",
abstract = "Styryl dyes, specifically LDS group dyes, are known solvatochromic and electrochromic probes for monitoring mitochondrial potential in cellular environments. However, the ability of these dyes to respond to fluctuations in viscosity, pH and temperature has not been established. In this study, we demonstrated that LDS 798 (also known as Styryl-11) can sense environmental viscosity (via fluorescence lifetime changes) as well as pH changes (ratiometric intensity change) in the absence of polarity variations. Polarity changes can be probed by spectral changes using LDS 798. Therefore, all properties of the media should be considered, when these types of dyes are used as electrochromic/solvatochromic sensors in cellular environments.",
author = "Hung Doan and Marlius Castillo and Micheline Bejjani and Zhangatay Nurekeyev and Dzyuba, {Sergei V.} and Ignacy Gryczynski and Zygmunt Gryczynski and Raut, {Sangram Limbaji}",
year = "2017",
month = "1",
day = "1",
doi = "10.1039/c7cp05874h",
language = "English",
volume = "19",
pages = "29934--29939",
journal = "Physical Chemistry Chemical Physics",
issn = "1463-9076",
publisher = "Royal Society of Chemistry",
number = "44",

}

Solvatochromic dye LDS 798 as microviscosity and pH probe. / Doan, Hung; Castillo, Marlius; Bejjani, Micheline; Nurekeyev, Zhangatay; Dzyuba, Sergei V.; Gryczynski, Ignacy; Gryczynski, Zygmunt; Raut, Sangram Limbaji.

In: Physical Chemistry Chemical Physics, Vol. 19, No. 44, 01.01.2017, p. 29934-29939.

Research output: Contribution to journalArticleResearchpeer-review

TY - JOUR

T1 - Solvatochromic dye LDS 798 as microviscosity and pH probe

AU - Doan, Hung

AU - Castillo, Marlius

AU - Bejjani, Micheline

AU - Nurekeyev, Zhangatay

AU - Dzyuba, Sergei V.

AU - Gryczynski, Ignacy

AU - Gryczynski, Zygmunt

AU - Raut, Sangram Limbaji

PY - 2017/1/1

Y1 - 2017/1/1

N2 - Styryl dyes, specifically LDS group dyes, are known solvatochromic and electrochromic probes for monitoring mitochondrial potential in cellular environments. However, the ability of these dyes to respond to fluctuations in viscosity, pH and temperature has not been established. In this study, we demonstrated that LDS 798 (also known as Styryl-11) can sense environmental viscosity (via fluorescence lifetime changes) as well as pH changes (ratiometric intensity change) in the absence of polarity variations. Polarity changes can be probed by spectral changes using LDS 798. Therefore, all properties of the media should be considered, when these types of dyes are used as electrochromic/solvatochromic sensors in cellular environments.

AB - Styryl dyes, specifically LDS group dyes, are known solvatochromic and electrochromic probes for monitoring mitochondrial potential in cellular environments. However, the ability of these dyes to respond to fluctuations in viscosity, pH and temperature has not been established. In this study, we demonstrated that LDS 798 (also known as Styryl-11) can sense environmental viscosity (via fluorescence lifetime changes) as well as pH changes (ratiometric intensity change) in the absence of polarity variations. Polarity changes can be probed by spectral changes using LDS 798. Therefore, all properties of the media should be considered, when these types of dyes are used as electrochromic/solvatochromic sensors in cellular environments.

UR - http://www.scopus.com/inward/record.url?scp=85034596446&partnerID=8YFLogxK

U2 - 10.1039/c7cp05874h

DO - 10.1039/c7cp05874h

M3 - Article

VL - 19

SP - 29934

EP - 29939

JO - Physical Chemistry Chemical Physics

JF - Physical Chemistry Chemical Physics

SN - 1463-9076

IS - 44

ER -

Doan H, Castillo M, Bejjani M, Nurekeyev Z, Dzyuba SV, Gryczynski I et al. Solvatochromic dye LDS 798 as microviscosity and pH probe. Physical Chemistry Chemical Physics. 2017 Jan 1;19(44):29934-29939. https://doi.org/10.1039/c7cp05874h