Single nucleotide polymorphism (SNP) typing is likely to be an adjunct forensic technology to be used when short tandem repeat (STR) typing fails to yield a result or when only a partial profile is obtained. It is anticipated that forensic SNP analyses will be applied to typing mtDNA, Y chromosome lineage analyses, characterizing highly degraded DNA samples, ssessing biogeographical ancestry, and typing for determining physical characteristics. As examples, three SNP typing strategies briefly described. They are SNaP shot™, SNPstream® Ultra High Throughput System, and electrospray ionization mass spectrometry. The latter approach offers certain advantages for SNP analysis, particularly so for mtDNA typing.
- DNA typing
- Electrospray ionization mass spectrometry
- Forensic science
- Primer extension
- SNaP shot™
- Single nucleotide polymorphism (SNP)
- Ultra High Throughput System