Abstract
Motivation: SNP-based kinship analysis with genome-wide relationship estimation and IBD segment analysis methods produces results that often require further downstream process- ing and manipulation. A dedicated software package that consistently and intuitively imple- ments this analysis functionality is needed. Results: Here we present the skater R package for SNP-based kinship analysis, testing, and evaluation with R. The skater package contains a suite of well-documented tools for importing, parsing, and analyzing pedigree data, performing relationship degree inference, benchmarking relationship degree classification, and summarizing IBD segment data. Availability: The skater package is implemented as an R package and is released under the MIT license at https://github.com/signaturescience/skater. Documentation is available at https://signaturescience.github.io/skater.
Original language | English |
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Article number | 18 |
Journal | F1000Research |
Volume | 11 |
DOIs | |
State | Published - 2022 |
Keywords
- Bioinformatics
- Genealogy
- Kinship
- R
- Relatedness
- SNPs
- Single nucleotide polymorphisms