Size exclusion chromatography with electrospray mass spectrometric detection

William J. Simonsick, Laszlo Prokai

Research output: Contribution to journalConference article

5 Scopus citations

Abstract

We have interfaced SEC with ESP/MS. The SEC reduces the total number of components entering the ESP/MS source compared of direct injection. SEC/ESP/MS couples a powerful chromatographic size separation technique with a sensitive absolute molecular weight detector. This is an ideal tool for complex mixture analysis. The successively acquired mass spectra contain narrow `cuts' of the overall distribution which simplify the analysis of polydisperse mixtures.

Original languageEnglish
Pages (from-to)412-413
Number of pages2
JournalPolymeric Materials Science and Engineering, Proceedings of the ACS Division of Polymeric Materials Science and Engineering
Volume69
StatePublished - 1 Dec 1993
EventProceedings of the American Chemical Society Division of Polymeric Materials - Science and Engineering - Chicago, IL, USA
Duration: 11 Jun 199311 Jun 1993

Fingerprint Dive into the research topics of 'Size exclusion chromatography with electrospray mass spectrometric detection'. Together they form a unique fingerprint.

  • Cite this