Sigma-1 receptor stimulation protects retinal ganglion cells from ischemia-like insult through the activation of extracellular-signal-regulated kinases 1/2

Keyphrases

• 1 Receptor 54%
• BD1047 9%
• Beta-tubulin 9%
• Calcein 9%
• Cell Death 27%
• Cell Survival 9%
• Co-treatment 9%
• ERK2 18%
• Ethidium homodimer-1 9%
• Extracellular Signal-regulated Kinase 1/2 100%
• Free Media 9%
• Immunoblotting 9%
• Immunofluorescence Staining 9%
• Immunopanning 9%
• Insults 100%
• Ischemia 100%
• MEK1 18%
• Mitogen-activated Protein Kinase 9%
• Neuroprotection 18%
• Neuroprotective 9%
• Neuroprotective Effect 9%
• Ocular Neurodegenerative Disease 9%
• Oxygen-glucose Deprivation/reoxygenation (OGD/R) 72%
• PD098059 18%
• Pentazocine 63%
• Phosphorylation 9%
• Primary Retinal Ganglion Cells 27%
• Protective Effect 9%
• Receptor 1 9%
• Receptor Agonist 9%
• Receptor Antagonist 9%
• Retinal Ganglion Cells 100%
• Sigma-1 Receptor 100%
• Sprague-Dawley Rats 9%
• Therapeutic Target 9%

Medicine and Dentistry

• 2 (2 Amino 3 Methoxyphenyl)chromone 14%
• Beta Tubulin 7%
• Calcein 7%
• Cell Death 21%
• Cell Survival 7%
• Degenerative Disease 7%
• Ethidium 7%
• Ganglion 100%
• Glucose 64%
• Homodimer 7%
• Immunoblotting 7%
• Immunofluorescence 7%
• Ischemia 100%
• Mitogen Activated Protein Kinase 3 100%
• Mitogen-Activated Protein Kinase 7%
• Neuroprotection 14%
• Neuroprotective Agent 14%
• Pentazocine 50%
• phosphorylation 7%
• Receptor 35%
• Receptor Antagonist 7%
• Sigma 1 Opiate Receptor 100%
• Therapeutic Target 7%

Neuroscience

• Beta Tubulin 7%
• Cell Death 21%
• Cell Survival 7%
• Glucose 64%
• Immunoblotting 7%
• Immunofluorescence 7%
• Ischemia 100%
• Mitogen Activated Protein Kinase 3 100%
• Mitogen-Activated Protein Kinase 7%
• Neurodegenerative Disorder 7%
• Neuroprotection 14%
• Neuroprotective Agent 14%
• Pentazocine 50%
• phosphorylation 7%
• Receptor 28%
• Receptor Agonists 7%
• Receptor Antagonist 7%
• Retinal Ganglion Cell 100%
• Sigma 1 Opiate Receptor 100%
• Staining Technique 14%