Self-reported racial discrimination, response to unfair treatment, and coronary calcification in asymptomatic adults - The North Texas Healthy Heart study

Roberto Cardarelli, Kathryn M. Cardarelli, Kimberly G. Fulda, Anna Espinoza, Clifton Cage, Jamboor Vishwanatha, Richard Young, Darryl N. Steele, Joan Carroll

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Abstract

Background. Accruing evidence supports the hypothesis that psychosocial factors are related to cardiovascular disease. However, a limited number of studies have investigated the pathophysiologic pathways through which these associations occur. The purpose of this study was to assess whether experiences of self-reported racial discrimination and reactions to unfair treatment were associated with coronary artery calcification (CAC), an indicator of subclinical coronary heart disease (CHD). Methods. This cross-sectional study recruited 571 subjects (45 years and older) who were asymptomatic of CHD from Fort Worth, Texas from 2006 to 2008. Subjects completed a questionnaire, a multi-slice computed tomography scan to assess for CAC presence (measured as Agatston score ≥0), and serum chemistries. Logistic regression was used to estimate odds ratios (ORs) and 95% confidence intervals (CIs) for the association between self-reported discrimination and CAC. Results were stratified by response to unfair treatment as it was found to significantly modify the relationship between discrimination and CAC. Results. Among those who passively responded to unfair treatment, the odds of having CAC present were approximately 3 times higher for those experiencing discrimination (OR, 2.95; 95% CI, 1.19-7.32) after adjusting for age, gender, race/ethnicity, education, body mass index, hyperlipidemia, smoking status, hypertension, diabetes, and first degree relative with heart disease. Conclusions. This is the first multi-racial/ethnic study to find racial discrimination associated with CAC, which differs based on how one responds to unfair treatment.

Original languageEnglish
Article number285
JournalBMC Public Health
Volume10
DOIs
StatePublished - 31 May 2010

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Racism
Coronary Vessels
Coronary Disease
Therapeutics
Odds Ratio
Confidence Intervals
Hyperlipidemias
Heart Diseases
Body Mass Index
Cardiovascular Diseases
Cross-Sectional Studies
Logistic Models
Smoking
Tomography
Psychology
Hypertension
Education
Serum

Cite this

@article{6e461a3252854f3a9d7d41e551b782ec,
title = "Self-reported racial discrimination, response to unfair treatment, and coronary calcification in asymptomatic adults - The North Texas Healthy Heart study",
abstract = "Background. Accruing evidence supports the hypothesis that psychosocial factors are related to cardiovascular disease. However, a limited number of studies have investigated the pathophysiologic pathways through which these associations occur. The purpose of this study was to assess whether experiences of self-reported racial discrimination and reactions to unfair treatment were associated with coronary artery calcification (CAC), an indicator of subclinical coronary heart disease (CHD). Methods. This cross-sectional study recruited 571 subjects (45 years and older) who were asymptomatic of CHD from Fort Worth, Texas from 2006 to 2008. Subjects completed a questionnaire, a multi-slice computed tomography scan to assess for CAC presence (measured as Agatston score ≥0), and serum chemistries. Logistic regression was used to estimate odds ratios (ORs) and 95{\%} confidence intervals (CIs) for the association between self-reported discrimination and CAC. Results were stratified by response to unfair treatment as it was found to significantly modify the relationship between discrimination and CAC. Results. Among those who passively responded to unfair treatment, the odds of having CAC present were approximately 3 times higher for those experiencing discrimination (OR, 2.95; 95{\%} CI, 1.19-7.32) after adjusting for age, gender, race/ethnicity, education, body mass index, hyperlipidemia, smoking status, hypertension, diabetes, and first degree relative with heart disease. Conclusions. This is the first multi-racial/ethnic study to find racial discrimination associated with CAC, which differs based on how one responds to unfair treatment.",
author = "Roberto Cardarelli and Cardarelli, {Kathryn M.} and Fulda, {Kimberly G.} and Anna Espinoza and Clifton Cage and Jamboor Vishwanatha and Richard Young and Steele, {Darryl N.} and Joan Carroll",
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doi = "10.1186/1471-2458-10-285",
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Self-reported racial discrimination, response to unfair treatment, and coronary calcification in asymptomatic adults - The North Texas Healthy Heart study. / Cardarelli, Roberto; Cardarelli, Kathryn M.; Fulda, Kimberly G.; Espinoza, Anna; Cage, Clifton; Vishwanatha, Jamboor; Young, Richard; Steele, Darryl N.; Carroll, Joan.

In: BMC Public Health, Vol. 10, 285, 31.05.2010.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Self-reported racial discrimination, response to unfair treatment, and coronary calcification in asymptomatic adults - The North Texas Healthy Heart study

AU - Cardarelli, Roberto

AU - Cardarelli, Kathryn M.

AU - Fulda, Kimberly G.

AU - Espinoza, Anna

AU - Cage, Clifton

AU - Vishwanatha, Jamboor

AU - Young, Richard

AU - Steele, Darryl N.

AU - Carroll, Joan

PY - 2010/5/31

Y1 - 2010/5/31

N2 - Background. Accruing evidence supports the hypothesis that psychosocial factors are related to cardiovascular disease. However, a limited number of studies have investigated the pathophysiologic pathways through which these associations occur. The purpose of this study was to assess whether experiences of self-reported racial discrimination and reactions to unfair treatment were associated with coronary artery calcification (CAC), an indicator of subclinical coronary heart disease (CHD). Methods. This cross-sectional study recruited 571 subjects (45 years and older) who were asymptomatic of CHD from Fort Worth, Texas from 2006 to 2008. Subjects completed a questionnaire, a multi-slice computed tomography scan to assess for CAC presence (measured as Agatston score ≥0), and serum chemistries. Logistic regression was used to estimate odds ratios (ORs) and 95% confidence intervals (CIs) for the association between self-reported discrimination and CAC. Results were stratified by response to unfair treatment as it was found to significantly modify the relationship between discrimination and CAC. Results. Among those who passively responded to unfair treatment, the odds of having CAC present were approximately 3 times higher for those experiencing discrimination (OR, 2.95; 95% CI, 1.19-7.32) after adjusting for age, gender, race/ethnicity, education, body mass index, hyperlipidemia, smoking status, hypertension, diabetes, and first degree relative with heart disease. Conclusions. This is the first multi-racial/ethnic study to find racial discrimination associated with CAC, which differs based on how one responds to unfair treatment.

AB - Background. Accruing evidence supports the hypothesis that psychosocial factors are related to cardiovascular disease. However, a limited number of studies have investigated the pathophysiologic pathways through which these associations occur. The purpose of this study was to assess whether experiences of self-reported racial discrimination and reactions to unfair treatment were associated with coronary artery calcification (CAC), an indicator of subclinical coronary heart disease (CHD). Methods. This cross-sectional study recruited 571 subjects (45 years and older) who were asymptomatic of CHD from Fort Worth, Texas from 2006 to 2008. Subjects completed a questionnaire, a multi-slice computed tomography scan to assess for CAC presence (measured as Agatston score ≥0), and serum chemistries. Logistic regression was used to estimate odds ratios (ORs) and 95% confidence intervals (CIs) for the association between self-reported discrimination and CAC. Results were stratified by response to unfair treatment as it was found to significantly modify the relationship between discrimination and CAC. Results. Among those who passively responded to unfair treatment, the odds of having CAC present were approximately 3 times higher for those experiencing discrimination (OR, 2.95; 95% CI, 1.19-7.32) after adjusting for age, gender, race/ethnicity, education, body mass index, hyperlipidemia, smoking status, hypertension, diabetes, and first degree relative with heart disease. Conclusions. This is the first multi-racial/ethnic study to find racial discrimination associated with CAC, which differs based on how one responds to unfair treatment.

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AN - SCOPUS:77952730075

VL - 10

JO - BMC Public Health

JF - BMC Public Health

SN - 1471-2458

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