Sample size estimation for survival outcomes in cluster-randomized studies with small cluster sizes

Amita K. Manatunga, Shande Chen

Research output: Contribution to journalArticle

13 Scopus citations

Abstract

We present a method for computing sample size for cluster-randomized studies involving a large number of clusters with relatively small numbers of observations within each cluster. For multivariate survival data, only the marginal bivariate distribution is assumed to be known. The validity of this assumption is also discussed.

Original languageEnglish
Pages (from-to)616-621
Number of pages6
JournalBiometrics
Volume56
Issue number2
DOIs
StatePublished - Jun 2000

Keywords

  • Cluster randomized
  • Clusters
  • Multivariate survival
  • Sample size
  • Survival

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