Abstract
Children with hematologic malignancies are at an increased risk of invasive fungal infections and a greater risk has been seen with exposure to building construction. Prophylaxis with high-dose (IV) liposomal amphotericin B (L-AmB) 10 mg/kg once weekly was initiated in our high risk children based on previous pharmacokinetic studies. This treatment regimen was associated with a 26% incidence of adverse infusion reactions.
Original language | English |
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Pages (from-to) | 835-836 |
Number of pages | 2 |
Journal | Pediatric Infectious Disease Journal |
Volume | 33 |
Issue number | 8 |
DOIs | |
State | Published - Aug 2014 |
Keywords
- Amphotericin B
- Prophylaxis
- Tolerability