Robust pulse wave velocity estimation by application of system identification to proximal and distal arterial waveforms

Da Xu, Kathy L. Ryan, Caroline A. Rickards, Guanqun Zhang, Victor A. Convertino, Ramakrishna Mukkamala

Research output: Chapter in Book/Report/Conference proceedingConference contribution

6 Scopus citations

Abstract

Pulse wave velocity (PWV) is a marker of arterial stiffness and may permit continuous, non-invasive, and cuff-less monitoring of blood pressure. Here, robust PWV estimation was sought by application of system identification to proximal and distal arterial waveforms. In this approach, the system that optimally couples the proximal waveform to the distal waveform is identified, and the time delay of this system is then used to calculate PWV. To demonstrate proof-of-concept, a standard identification technique was applied to non-invasive impedance cardiography and peripheral arterial blood pressure waveforms from six humans subjected to progressive reductions in central blood volume induced by lower body negative pressure. This technique estimated diastolic pressure with an overall root-mean-squared-error of 5.2 mmHg. For comparison, the conventional detection method for estimating PWV yielded a corresponding error of 8.3 mmHg.

Original languageEnglish
Title of host publication2010 Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC'10
Pages3559-3562
Number of pages4
DOIs
StatePublished - 1 Dec 2010
Event2010 32nd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC'10 - Buenos Aires, Argentina
Duration: 31 Aug 20104 Sep 2010

Publication series

Name2010 Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC'10

Other

Other2010 32nd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC'10
CountryArgentina
CityBuenos Aires
Period31/08/104/09/10

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    Xu, D., Ryan, K. L., Rickards, C. A., Zhang, G., Convertino, V. A., & Mukkamala, R. (2010). Robust pulse wave velocity estimation by application of system identification to proximal and distal arterial waveforms. In 2010 Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC'10 (pp. 3559-3562). [5627718] (2010 Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC'10). https://doi.org/10.1109/IEMBS.2010.5627718