Resting metabolic rate is not reduced in obese adults with down syndrome

Bo Fernhall, Arturo Figueroa, Scott Collier, Styliani Goulopoulou, Ifigenia Giannopoulou, Tracy Baynard

Research output: Contribution to journalArticleResearchpeer-review

20 Citations (Scopus)

Abstract

Resting metabolic rate (RMR) of 22 individuals with Down syndrome was compared to that of 20 nondisabled control individuals of similar age (25.7 and 27.4 years, respectively). Using a ventilated hood system, we measured RMR in the early morning after an overnight fast. Peak aerobic capacity (VO2peak) and body composition were also determined. Resting metabolic rate was not different between groups. Adjusting RMR for body weight or body surface area did not change these findings. Using stepwise regression for the total population and each subgroup, we found that only body surface area was a significant predictor of RMR. These data show that individuals with Down syndrome do not have lower RMR than their nondisabled peers, suggesting that reduced RMR does not explain the high incidence of obesity in this population.

Original languageEnglish
JournalMental Retardation
Volume43
Issue number6
StatePublished - 1 Dec 2005

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Basal Metabolism
Down Syndrome
body weight
Body Surface Area
incidence
regression
Body Composition
Population
Group
Obesity
Body Weight
Incidence

Cite this

Fernhall, B., Figueroa, A., Collier, S., Goulopoulou, S., Giannopoulou, I., & Baynard, T. (2005). Resting metabolic rate is not reduced in obese adults with down syndrome. Mental Retardation, 43(6).
Fernhall, Bo ; Figueroa, Arturo ; Collier, Scott ; Goulopoulou, Styliani ; Giannopoulou, Ifigenia ; Baynard, Tracy. / Resting metabolic rate is not reduced in obese adults with down syndrome. In: Mental Retardation. 2005 ; Vol. 43, No. 6.
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Fernhall, B, Figueroa, A, Collier, S, Goulopoulou, S, Giannopoulou, I & Baynard, T 2005, 'Resting metabolic rate is not reduced in obese adults with down syndrome', Mental Retardation, vol. 43, no. 6.

Resting metabolic rate is not reduced in obese adults with down syndrome. / Fernhall, Bo; Figueroa, Arturo; Collier, Scott; Goulopoulou, Styliani; Giannopoulou, Ifigenia; Baynard, Tracy.

In: Mental Retardation, Vol. 43, No. 6, 01.12.2005.

Research output: Contribution to journalArticleResearchpeer-review

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AU - Goulopoulou, Styliani

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AU - Baynard, Tracy

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AB - Resting metabolic rate (RMR) of 22 individuals with Down syndrome was compared to that of 20 nondisabled control individuals of similar age (25.7 and 27.4 years, respectively). Using a ventilated hood system, we measured RMR in the early morning after an overnight fast. Peak aerobic capacity (VO2peak) and body composition were also determined. Resting metabolic rate was not different between groups. Adjusting RMR for body weight or body surface area did not change these findings. Using stepwise regression for the total population and each subgroup, we found that only body surface area was a significant predictor of RMR. These data show that individuals with Down syndrome do not have lower RMR than their nondisabled peers, suggesting that reduced RMR does not explain the high incidence of obesity in this population.

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Fernhall B, Figueroa A, Collier S, Goulopoulou S, Giannopoulou I, Baynard T. Resting metabolic rate is not reduced in obese adults with down syndrome. Mental Retardation. 2005 Dec 1;43(6).