Resolution of Amino Acid Enantiomers by Ligand Exchange Chromatography on a New Chiral Packing

Husheng Yan; Xiaohui Cheng; Aiguo Ni; Binglin He

doi:10.1080/10826079308019570

Resolution of Amino Acid Enantiomers by Ligand Exchange Chromatography on a New Chiral Packing

Husheng Yan, Xiaohui Cheng, Aiguo Ni, Binglin He

Research output: Contribution to journal › Article › peer-review

8 Scopus citations

Abstract

Resolution of α-amino acid enantiomers by ligand exchange chromatography on a new chiral packing, which the chiral ligands were linked onto a hydrophilic polymeric matrix through long spacers, was studied. The packing had high enantioselectivity for most of the amino acids tested. The mechanism of the resolution was discussed. The semi- preparative scale resolution was made.

Original language	English
Pages (from-to)	1045-1055
Number of pages	11
Journal	Journal of Liquid Chromatography
Volume	16
Issue number	5
DOIs	https://doi.org/10.1080/10826079308019570
State	Published - 1 Apr 1993

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title = "Resolution of Amino Acid Enantiomers by Ligand Exchange Chromatography on a New Chiral Packing",

abstract = "Resolution of α-amino acid enantiomers by ligand exchange chromatography on a new chiral packing, which the chiral ligands were linked onto a hydrophilic polymeric matrix through long spacers, was studied. The packing had high enantioselectivity for most of the amino acids tested. The mechanism of the resolution was discussed. The semi- preparative scale resolution was made.",

author = "Husheng Yan and Xiaohui Cheng and Aiguo Ni and Binglin He",

year = "1993",

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AU - Yan, Husheng

AU - Cheng, Xiaohui

AU - Ni, Aiguo

AU - He, Binglin

PY - 1993/4/1

Y1 - 1993/4/1

N2 - Resolution of α-amino acid enantiomers by ligand exchange chromatography on a new chiral packing, which the chiral ligands were linked onto a hydrophilic polymeric matrix through long spacers, was studied. The packing had high enantioselectivity for most of the amino acids tested. The mechanism of the resolution was discussed. The semi- preparative scale resolution was made.

AB - Resolution of α-amino acid enantiomers by ligand exchange chromatography on a new chiral packing, which the chiral ligands were linked onto a hydrophilic polymeric matrix through long spacers, was studied. The packing had high enantioselectivity for most of the amino acids tested. The mechanism of the resolution was discussed. The semi- preparative scale resolution was made.

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U2 - 10.1080/10826079308019570

DO - 10.1080/10826079308019570

M3 - Article

AN - SCOPUS:0027538584

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SP - 1045

EP - 1055

JO - Journal of Liquid Chromatography

JF - Journal of Liquid Chromatography

SN - 0148-3919

IS - 5

ER -

Resolution of Amino Acid Enantiomers by Ligand Exchange Chromatography on a New Chiral Packing

Abstract

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