Resolution of Amino Acid Enantiomers by Ligand Exchange Chromatography on a New Chiral Packing

Husheng Yan, Xiaohui Cheng, Aiguo Ni, Binglin He

Research output: Contribution to journalArticle

8 Scopus citations

Abstract

Resolution of α-amino acid enantiomers by ligand exchange chromatography on a new chiral packing, which the chiral ligands were linked onto a hydrophilic polymeric matrix through long spacers, was studied. The packing had high enantioselectivity for most of the amino acids tested. The mechanism of the resolution was discussed. The semi- preparative scale resolution was made.

Original languageEnglish
Pages (from-to)1045-1055
Number of pages11
JournalJournal of Liquid Chromatography
Volume16
Issue number5
DOIs
StatePublished - 1 Apr 1993

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