Abstract
Resolution of α-amino acid enantiomers by ligand exchange chromatography on a new chiral packing, which the chiral ligands were linked onto a hydrophilic polymeric matrix through long spacers, was studied. The packing had high enantioselectivity for most of the amino acids tested. The mechanism of the resolution was discussed. The semi- preparative scale resolution was made.
Original language | English |
---|---|
Pages (from-to) | 1045-1055 |
Number of pages | 11 |
Journal | Journal of Liquid Chromatography |
Volume | 16 |
Issue number | 5 |
DOIs | |
State | Published - 1 Apr 1993 |