Relationship between single‐and multi‐locus measures of gene diversity in a subdivided population

Ranajit Chakraborty

doi:10.1111/j.1469-1809.1980.tb01576.x

Relationship between single‐and multi‐locus measures of gene diversity in a subdivided population

Ranajit Chakraborty

Graduate School of Biomedical Sciences

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Abstract

A mathematical relationship between the coefficient of gene diversity as derived from average single locus statistics and Smouse and Spielman's multi‐locus measure is established under the assumption of linkage equilibrium in a substructured population. A formula for estimating the average time of split of subpopulations from such gene diversity is also derived for the multi‐locus criterion. Unlike the estimate derived for single‐locus criterion, this estimate does not explicitely depend on the number of subpopulations. The method is illustrated with data on allozyme studies from the South American Indian populations.

Original language	English
Pages (from-to)	423-428
Number of pages	6
Journal	Annals of Human Genetics
Volume	43
Issue number	4
DOIs	https://doi.org/10.1111/j.1469-1809.1980.tb01576.x
State	Published - 1 Jan 1980

Access to Document

10.1111/j.1469-1809.1980.tb01576.x

Fingerprint Dive into the research topics of 'Relationship between single‐and multi‐locus measures of gene diversity in a subdivided population'. Together they form a unique fingerprint.

Cite this

@article{094479b77cf44bb28e2ea28c933497a4,

title = "Relationship between single‐and multi‐locus measures of gene diversity in a subdivided population",

abstract = "A mathematical relationship between the coefficient of gene diversity as derived from average single locus statistics and Smouse and Spielman's multi‐locus measure is established under the assumption of linkage equilibrium in a substructured population. A formula for estimating the average time of split of subpopulations from such gene diversity is also derived for the multi‐locus criterion. Unlike the estimate derived for single‐locus criterion, this estimate does not explicitely depend on the number of subpopulations. The method is illustrated with data on allozyme studies from the South American Indian populations.",

author = "Ranajit Chakraborty",

year = "1980",

month = jan,

day = "1",

doi = "10.1111/j.1469-1809.1980.tb01576.x",

language = "English",

volume = "43",

pages = "423--428",

journal = "Annals of Human Genetics",

issn = "0003-4800",

publisher = "Wiley-Blackwell Publishing Ltd",

number = "4",

}

TY - JOUR

T1 - Relationship between single‐and multi‐locus measures of gene diversity in a subdivided population

AU - Chakraborty, Ranajit

PY - 1980/1/1

Y1 - 1980/1/1

N2 - A mathematical relationship between the coefficient of gene diversity as derived from average single locus statistics and Smouse and Spielman's multi‐locus measure is established under the assumption of linkage equilibrium in a substructured population. A formula for estimating the average time of split of subpopulations from such gene diversity is also derived for the multi‐locus criterion. Unlike the estimate derived for single‐locus criterion, this estimate does not explicitely depend on the number of subpopulations. The method is illustrated with data on allozyme studies from the South American Indian populations.

AB - A mathematical relationship between the coefficient of gene diversity as derived from average single locus statistics and Smouse and Spielman's multi‐locus measure is established under the assumption of linkage equilibrium in a substructured population. A formula for estimating the average time of split of subpopulations from such gene diversity is also derived for the multi‐locus criterion. Unlike the estimate derived for single‐locus criterion, this estimate does not explicitely depend on the number of subpopulations. The method is illustrated with data on allozyme studies from the South American Indian populations.

UR - http://www.scopus.com/inward/record.url?scp=0018835969&partnerID=8YFLogxK

U2 - 10.1111/j.1469-1809.1980.tb01576.x

DO - 10.1111/j.1469-1809.1980.tb01576.x

M3 - Article

C2 - 7396414

AN - SCOPUS:0018835969

VL - 43

SP - 423

EP - 428

JO - Annals of Human Genetics

JF - Annals of Human Genetics

SN - 0003-4800

IS - 4

ER -

Relationship between single‐and multi‐locus measures of gene diversity in a subdivided population

Abstract

Access to Document

Other files and links

Cite this