Relationship between single‐and multi‐locus measures of gene diversity in a subdivided population

Ranajit Chakraborty

Research output: Contribution to journalArticle

3 Scopus citations

Abstract

A mathematical relationship between the coefficient of gene diversity as derived from average single locus statistics and Smouse and Spielman's multi‐locus measure is established under the assumption of linkage equilibrium in a substructured population. A formula for estimating the average time of split of subpopulations from such gene diversity is also derived for the multi‐locus criterion. Unlike the estimate derived for single‐locus criterion, this estimate does not explicitely depend on the number of subpopulations. The method is illustrated with data on allozyme studies from the South American Indian populations.

Original languageEnglish
Pages (from-to)423-428
Number of pages6
JournalAnnals of Human Genetics
Volume43
Issue number4
DOIs
StatePublished - 1 Jan 1980

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