Reduction of photobleaching and photodamage in single molecule detection: Observing single actin monomer in skeletal myofibrils

Engineering & Materials Science

• Photobleaching 100%
• Monomers 67%
• Molecules 55%
• Fluorescence 52%
• Monolayers 45%
• Fluorophores 38%
• Muscle 32%
• Excited states 19%
• Glass 18%
• Silver nanoparticles 16%
• Laser beams 13%
• Nanoparticles 11%
• Cells 11%
• Electric fields 10%
• Proteins 10%
• Oxygen 9%
• Detectors 8%
• Coatings 8%
• Substrates 8%

Chemical Compounds

• Single Molecule Detection 78%
• Photobleaching 67%
• Monomer 33%
• Monolayer 32%
• Fluorescence Lifetime 29%
• Reduction 26%
• Phalloidin 23%
• Time 20%
• Fluorescence 16%
• Glass Substrate 14%
• Silver Nanoparticle 12%
• Electric Field 12%
• Excited State 11%
• Molecule 9%
• Glass 9%
• Coating Agent 8%
• Nanoparticle 7%
• Dioxygen 6%
• Protein 5%

Physics & Astronomy

• monomers 52%
• muscles 36%
• fluorescence 33%
• molecules 30%
• cells 24%
• damage 16%
• life (durability) 15%
• nanoparticles 15%
• glass 13%
• attack 12%
• assemblies 11%
• low concentrations 10%
• silver 9%
• proteins 9%
• laser beams 8%
• coatings 7%
• causes 6%
• oxygen 6%
• electric fields 6%
• decay 6%
• detectors 6%
• excitation 5%