Reduced haloperidol/haloperidol ratios after oral haloperidol and decanoate administration in schizophrenics

Chang Weh-Ho; Lin Shih-Ku; Juang Dong-Juiing; Chen Li-Chen; Yang Chih-Hsien; Hu Wei-Herng; Chien Ching-Piao; Yw Francis Lam; Michael W. Jann

doi:10.1016/0278-5846(93)90035-Q

Reduced haloperidol/haloperidol ratios after oral haloperidol and decanoate administration in schizophrenics

Chang Weh-Ho, Lin Shih-Ku, Juang Dong-Juiing, Chen Li-Chen, Yang Chih-Hsien, Hu Wei-Herng, Chien Ching-Piao, Yw Francis Lam, Michael W. Jann

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Abstract

1. Haloperidol and reduced haloperidol plasma concentrations were measured in thirteen stable schizophrenic patients that received both oral haloperidol and haloperidol decanoate. 2. Significant correlations between reduced haloperidol/haloperidol ratios from oral haloperidol and haloperidol decanoate occurred at week two and week 16, respectively. 3. The formation of RH was consistent during haloperidol decanoate treatment.

Original language	English
Pages (from-to)	IN1-IN2,105-112
Journal	Progress in Neuropsychopharmacology and Biological Psychiatry
Volume	17
Issue number	1
DOIs	https://doi.org/10.1016/0278-5846(93)90035-Q
State	Published - Jan 1993

Keywords

RH/HL ratios
haloperidol
plasma concentrations
reduced haloperidol

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10.1016/0278-5846(93)90035-Q

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Weh-Ho, C., Shih-Ku, L., Dong-Juiing, J., Li-Chen, C., Chih-Hsien, Y., Wei-Herng, H., Ching-Piao, C., Lam, Y. F., & Jann, M. W. (1993). Reduced haloperidol/haloperidol ratios after oral haloperidol and decanoate administration in schizophrenics. Progress in Neuropsychopharmacology and Biological Psychiatry, 17(1), IN1-IN2,105-112. https://doi.org/10.1016/0278-5846(93)90035-Q

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title = "Reduced haloperidol/haloperidol ratios after oral haloperidol and decanoate administration in schizophrenics",

abstract = "1. Haloperidol and reduced haloperidol plasma concentrations were measured in thirteen stable schizophrenic patients that received both oral haloperidol and haloperidol decanoate. 2. Significant correlations between reduced haloperidol/haloperidol ratios from oral haloperidol and haloperidol decanoate occurred at week two and week 16, respectively. 3. The formation of RH was consistent during haloperidol decanoate treatment.",

keywords = "RH/HL ratios, haloperidol, plasma concentrations, reduced haloperidol",

author = "Chang Weh-Ho and Lin Shih-Ku and Juang Dong-Juiing and Chen Li-Chen and Yang Chih-Hsien and Hu Wei-Herng and Chien Ching-Piao and Lam, {Yw Francis} and Jann, {Michael W.}",

year = "1993",

month = jan,

doi = "10.1016/0278-5846(93)90035-Q",

language = "English",

volume = "17",

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journal = "Progress in Neuropsychopharmacology and Biological Psychiatry",

issn = "0278-5846",

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number = "1",

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Weh-Ho, C, Shih-Ku, L, Dong-Juiing, J, Li-Chen, C, Chih-Hsien, Y, Wei-Herng, H, Ching-Piao, C, Lam, YF & Jann, MW 1993, 'Reduced haloperidol/haloperidol ratios after oral haloperidol and decanoate administration in schizophrenics', Progress in Neuropsychopharmacology and Biological Psychiatry, vol. 17, no. 1, pp. IN1-IN2,105-112. https://doi.org/10.1016/0278-5846(93)90035-Q

TY - JOUR

T1 - Reduced haloperidol/haloperidol ratios after oral haloperidol and decanoate administration in schizophrenics

AU - Weh-Ho, Chang

AU - Shih-Ku, Lin

AU - Dong-Juiing, Juang

AU - Li-Chen, Chen

AU - Chih-Hsien, Yang

AU - Wei-Herng, Hu

AU - Ching-Piao, Chien

AU - Lam, Yw Francis

AU - Jann, Michael W.

PY - 1993/1

Y1 - 1993/1

N2 - 1. Haloperidol and reduced haloperidol plasma concentrations were measured in thirteen stable schizophrenic patients that received both oral haloperidol and haloperidol decanoate. 2. Significant correlations between reduced haloperidol/haloperidol ratios from oral haloperidol and haloperidol decanoate occurred at week two and week 16, respectively. 3. The formation of RH was consistent during haloperidol decanoate treatment.

AB - 1. Haloperidol and reduced haloperidol plasma concentrations were measured in thirteen stable schizophrenic patients that received both oral haloperidol and haloperidol decanoate. 2. Significant correlations between reduced haloperidol/haloperidol ratios from oral haloperidol and haloperidol decanoate occurred at week two and week 16, respectively. 3. The formation of RH was consistent during haloperidol decanoate treatment.

KW - RH/HL ratios

KW - haloperidol

KW - plasma concentrations

KW - reduced haloperidol

UR - http://www.scopus.com/inward/record.url?scp=29944440187&partnerID=8YFLogxK

U2 - 10.1016/0278-5846(93)90035-Q

DO - 10.1016/0278-5846(93)90035-Q

M3 - Article

C2 - 8416597

AN - SCOPUS:29944440187

SN - 0278-5846

VL - 17

SP - IN1-IN2,105-112

JO - Progress in Neuropsychopharmacology and Biological Psychiatry

JF - Progress in Neuropsychopharmacology and Biological Psychiatry

IS - 1

ER -

Reduced haloperidol/haloperidol ratios after oral haloperidol and decanoate administration in schizophrenics

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Keywords

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