Recombinant Human Hemoglobin: Modification of the Polarity of the β-Heme Pocket by a Valine⁶⁷(E11) → Threonine Mutation

Keyphrases

• Recombinant Human 100%
• Threonine 100%
• Hemoglobin 100%
• Human Hemoglobin 100%
• Heme 100%
• O2 Binding 66%
• Oxygenation 66%
• T-states 66%
• CO Binding 66%
• Association Rate Constant 66%
• Fold Increase 33%
• Oxygen Binding 33%
• Kinetic Measurements 33%
• Rate of Increase 33%
• Dissociation Constant 33%
• Ligand Binding 33%
• Water Molecule 33%
• Ligation 33%
• Absorption Spectra 33%
• Bohr Phenomenon 33%
• Two-state Model 33%
• Functional Traits 33%
• Mutagenesis 33%
• O2 Dissociation 33%
• Ferrous Iron 33%
• Deoxyhemoglobin 33%
• Valine 33%
• Large Conformational Changes 33%
• Equilibrium Constant 33%
• Binding Curve 33%
• Equilibrium Measurements 33%
• CD Spectra 33%
• Gene Expression System 33%
• O2 Affinity 33%
• CO Dissociation 33%
• R State 33%
• Dissociation Rate Constant 33%
• Curve-based 33%
• Equilibrium Association Constant 33%
• Thermodynamic Analysis 33%
• J-protein 33%
• Iron Atom 33%
• Isosteric 33%

Biochemistry, Genetics and Molecular Biology

• Wild Type 100%
• Oxygenation 100%
• Equilibrium Constant 100%
• Association Rate Constant 100%
• Threonine 100%
• Conformational Change 50%
• Ligand Binding 50%
• Bohr Effect 50%
• Absorption 50%
• Gene Expression System 50%
• Mutagenesis 50%
• Dissociation Constant 50%
• Oxygen Affinity 50%
• Dissociation Rate Constant 50%
• Valine 50%