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Protein kinase Cε confers resistance of MCF-7 cells to TRAIL by Akt-dependent activation of Hdm2 and downregulation of p53
E. Shankar, U. Sivaprasad,
A. Basu
School of Biomedical Sciences
Microbiology, Immunology & Genetics
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peer-review
38
Scopus citations
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Medicine & Life Sciences
TNF-Related Apoptosis-Inducing Ligand
100%
MCF-7 Cells
74%
Protein Kinase C
65%
Down-Regulation
48%
Apoptosis
26%
Cell Death
13%
Phosphorylation
11%
Tumor Suppressor Protein p53
11%
Breast Neoplasms
11%
Tumor Necrosis Factor Receptors
9%
DNA Damage
7%
Small Interfering RNA
7%
Tumor Necrosis Factor-alpha
6%
Ligands
6%
Messenger RNA
4%
Proteins
3%