Properdin factor B in black Type 1 (insulin-dependent) diabetic patients

Bruce Budowle, P. J. Reitnauer, B. O. Barger, R. C.P. Go, J. M. Roseman, R. T. Acton

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

The properdin factor B(Bf) variant F1 was found in 20% of 70 black patients with Type 1 (insulindependent) diabetes compared with 7.3% of 165 control subjects, yielding a significant relative risk of 3.1. In addition, the BfF allele was negatively associated with Type 1 diabetes among blacks, resulting in a relative risk of 0.4. The data suggest that Type 1 diabetes in black Americans may be partially due to admixture of Caucasoid genes.

Original languageEnglish
Pages (from-to)483-485
Number of pages3
JournalDiabetologia
Volume22
Issue number6
DOIs
StatePublished - 1 Jun 1982

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Complement Factor B
Type 1 Diabetes Mellitus
Insulin
Alleles
Genes

Keywords

  • Properdin factor B
  • Type 1 diabetes
  • black Americans

Cite this

Budowle, B., Reitnauer, P. J., Barger, B. O., Go, R. C. P., Roseman, J. M., & Acton, R. T. (1982). Properdin factor B in black Type 1 (insulin-dependent) diabetic patients. Diabetologia, 22(6), 483-485. https://doi.org/10.1007/BF00282595
Budowle, Bruce ; Reitnauer, P. J. ; Barger, B. O. ; Go, R. C.P. ; Roseman, J. M. ; Acton, R. T. / Properdin factor B in black Type 1 (insulin-dependent) diabetic patients. In: Diabetologia. 1982 ; Vol. 22, No. 6. pp. 483-485.
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Budowle, B, Reitnauer, PJ, Barger, BO, Go, RCP, Roseman, JM & Acton, RT 1982, 'Properdin factor B in black Type 1 (insulin-dependent) diabetic patients', Diabetologia, vol. 22, no. 6, pp. 483-485. https://doi.org/10.1007/BF00282595

Properdin factor B in black Type 1 (insulin-dependent) diabetic patients. / Budowle, Bruce; Reitnauer, P. J.; Barger, B. O.; Go, R. C.P.; Roseman, J. M.; Acton, R. T.

In: Diabetologia, Vol. 22, No. 6, 01.06.1982, p. 483-485.

Research output: Contribution to journalArticle

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Budowle B, Reitnauer PJ, Barger BO, Go RCP, Roseman JM, Acton RT. Properdin factor B in black Type 1 (insulin-dependent) diabetic patients. Diabetologia. 1982 Jun 1;22(6):483-485. https://doi.org/10.1007/BF00282595