Properdin factor B in black Type 1 (insulin-dependent) diabetic patients

B. Budowle; P. J. Reitnauer; B. O. Barger; R. C.P. Go; J. M. Roseman; R. T. Acton

doi:10.1007/BF00282595

Properdin factor B in black Type 1 (insulin-dependent) diabetic patients

B. Budowle, P. J. Reitnauer, B. O. Barger, R. C.P. Go, J. M. Roseman, R. T. Acton

Research output: Contribution to journal › Article › peer-review

Abstract

The properdin factor B(Bf) variant F1 was found in 20% of 70 black patients with Type 1 (insulindependent) diabetes compared with 7.3% of 165 control subjects, yielding a significant relative risk of 3.1. In addition, the BfF allele was negatively associated with Type 1 diabetes among blacks, resulting in a relative risk of 0.4. The data suggest that Type 1 diabetes in black Americans may be partially due to admixture of Caucasoid genes.

Original language	English
Pages (from-to)	483-485
Number of pages	3
Journal	Diabetologia
Volume	22
Issue number	6
DOIs	https://doi.org/10.1007/BF00282595
State	Published - Jun 1982

Keywords

Properdin factor B
Type 1 diabetes
black Americans

Access to Document

10.1007/BF00282595

Cite this

@article{f06f95d251204c1cbada81294141099d,

title = "Properdin factor B in black Type 1 (insulin-dependent) diabetic patients",

abstract = "The properdin factor B(Bf) variant F1 was found in 20% of 70 black patients with Type 1 (insulindependent) diabetes compared with 7.3% of 165 control subjects, yielding a significant relative risk of 3.1. In addition, the BfF allele was negatively associated with Type 1 diabetes among blacks, resulting in a relative risk of 0.4. The data suggest that Type 1 diabetes in black Americans may be partially due to admixture of Caucasoid genes.",

keywords = "Properdin factor B, Type 1 diabetes, black Americans",

author = "B. Budowle and Reitnauer, {P. J.} and Barger, {B. O.} and Go, {R. C.P.} and Roseman, {J. M.} and Acton, {R. T.}",

year = "1982",

month = jun,

doi = "10.1007/BF00282595",

language = "English",

volume = "22",

pages = "483--485",

journal = "Diabetologia",

issn = "0012-186X",

publisher = "Springer Verlag",

number = "6",

}

TY - JOUR

T1 - Properdin factor B in black Type 1 (insulin-dependent) diabetic patients

AU - Budowle, B.

AU - Reitnauer, P. J.

AU - Barger, B. O.

AU - Go, R. C.P.

AU - Roseman, J. M.

AU - Acton, R. T.

PY - 1982/6

Y1 - 1982/6

N2 - The properdin factor B(Bf) variant F1 was found in 20% of 70 black patients with Type 1 (insulindependent) diabetes compared with 7.3% of 165 control subjects, yielding a significant relative risk of 3.1. In addition, the BfF allele was negatively associated with Type 1 diabetes among blacks, resulting in a relative risk of 0.4. The data suggest that Type 1 diabetes in black Americans may be partially due to admixture of Caucasoid genes.

AB - The properdin factor B(Bf) variant F1 was found in 20% of 70 black patients with Type 1 (insulindependent) diabetes compared with 7.3% of 165 control subjects, yielding a significant relative risk of 3.1. In addition, the BfF allele was negatively associated with Type 1 diabetes among blacks, resulting in a relative risk of 0.4. The data suggest that Type 1 diabetes in black Americans may be partially due to admixture of Caucasoid genes.

KW - Properdin factor B

KW - Type 1 diabetes

KW - black Americans

UR - http://www.scopus.com/inward/record.url?scp=0020055076&partnerID=8YFLogxK

U2 - 10.1007/BF00282595

DO - 10.1007/BF00282595

M3 - Article

C2 - 7049805

AN - SCOPUS:0020055076

SN - 0012-186X

VL - 22

SP - 483

EP - 485

JO - Diabetologia

JF - Diabetologia

IS - 6

ER -

Properdin factor B in black Type 1 (insulin-dependent) diabetic patients

Abstract

Keywords

Access to Document

Other files and links

Fingerprint

Cite this