Abstract
The properdin factor B(Bf) variant F1 was found in 20% of 70 black patients with Type 1 (insulindependent) diabetes compared with 7.3% of 165 control subjects, yielding a significant relative risk of 3.1. In addition, the BfF allele was negatively associated with Type 1 diabetes among blacks, resulting in a relative risk of 0.4. The data suggest that Type 1 diabetes in black Americans may be partially due to admixture of Caucasoid genes.
Original language | English |
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Pages (from-to) | 483-485 |
Number of pages | 3 |
Journal | Diabetologia |
Volume | 22 |
Issue number | 6 |
DOIs | |
State | Published - Jun 1982 |
Keywords
- Properdin factor B
- Type 1 diabetes
- black Americans