Prediction of Protein-Destabilizing Polymorphisms by Manual Curation with Protein Structure

Keyphrases

• Single nucleotide Polymorphism 100%
• Polymorphism 100%
• Protein Structure 100%
• Manual Curation 100%
• Premature Termination 66%
• Frameshift 66%
• Sequence Polymorphism 66%
• Protein Destabilization 66%
• Human Disease 33%
• Nonsense 33%
• Large Set 33%
• Protein Function 33%
• Truncated Protein 33%
• Protein Database 33%
• Disease Genes 33%
• Single Amino Acid Substitution 33%
• Database Annotation 33%
• Protein Sequence 33%
• Pathological Effect 33%
• Destabilization Mechanism 33%
• Nonsense-mediated Decay 33%
• Insertion or Deletion 33%
• Graphical Presentation 33%
• Manual Annotation 33%

Biochemistry, Genetics and Molecular Biology

• Single-Nucleotide Polymorphism 100%
• Indel 100%
• Protein Structure 100%
• Peptide Sequence 33%
• Genetic Disorder 33%
• Protein Database 33%
• Amino Acid Substitution 33%
• Nonsense-Mediated Decay 33%