Preclinical Efficacy of Anecortave Acetate

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Abstract

Anecortave acetate is a unique ocular angiostatic cortisene that has broad-based anti-angiogenic activity in 14 different preclinical models of neovascularization, across multiple species and inducers of neovascularization. Anecortave acetate is being tested clinically for inhibition of choroidal neovascularization associated with age-related macular degeneration.

Original languageEnglish
Pages (from-to)S41-S48
JournalSurvey of Ophthalmology
Volume52
Issue number1 SUPPL.
DOIs
StatePublished - 1 Jan 2007

Keywords

  • age-related macular degeneration
  • anecortave acetate
  • choroidal neovascularization
  • efficacy
  • preclinical

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