TY - JOUR
T1 - Pre-Exposure Prophylaxis (PrEP) for HIV Infection in Cisgender and Transgender Women in the U.S.
T2 - A Narrative Review of the Literature
AU - Baldwin, Aleta
AU - Light, Brenda
AU - Allison, Waridibo E.
N1 - Funding Information:
The authors would like to thank Charlotte Georgiou, Morgan Bayless, Jeanette Curtain, and Dorothy Nelson for their assistance.
Publisher Copyright:
© 2021, The Author(s).
PY - 2021/5
Y1 - 2021/5
N2 - Using a socioecological approach, this review describes the peer-reviewed literature on oral pre-exposure prophylaxis (PrEP) among both cisgender (cis women) and transgender women (trans women) in the U.S. A search of the PubMed database and HIV-related conference abstracts generated over 2,200 articles and abstracts. Of these, 103 fulfilled review inclusion criteria. Most of the existing research presents findings on individual-level factors associated with PrEP use such as willingness and perceived barriers. There was far less investigation of factors related to PrEP at more distal ecological levels. Though trans women are at greater risk of HIV infection than cisgender women, less is known about this population group with respect to PrEP despite their inclusion in many major clinical trials. Further, the literature is characterized by a persistent conflation of sex and gender which makes it difficult to accurately assess the reviewed research on HIV prevention and PrEP apart from risk group. Informed by these findings, we highlight specific opportunities to improve access to PrEP and reduce socioecological barriers to PrEP care engagement for cisgender and transgender women.
AB - Using a socioecological approach, this review describes the peer-reviewed literature on oral pre-exposure prophylaxis (PrEP) among both cisgender (cis women) and transgender women (trans women) in the U.S. A search of the PubMed database and HIV-related conference abstracts generated over 2,200 articles and abstracts. Of these, 103 fulfilled review inclusion criteria. Most of the existing research presents findings on individual-level factors associated with PrEP use such as willingness and perceived barriers. There was far less investigation of factors related to PrEP at more distal ecological levels. Though trans women are at greater risk of HIV infection than cisgender women, less is known about this population group with respect to PrEP despite their inclusion in many major clinical trials. Further, the literature is characterized by a persistent conflation of sex and gender which makes it difficult to accurately assess the reviewed research on HIV prevention and PrEP apart from risk group. Informed by these findings, we highlight specific opportunities to improve access to PrEP and reduce socioecological barriers to PrEP care engagement for cisgender and transgender women.
KW - Cisgender women
KW - Gender
KW - HIV prevention
KW - PrEP
KW - Pre-exposure prophylaxis
KW - Transgender women
UR - http://www.scopus.com/inward/record.url?scp=85107387691&partnerID=8YFLogxK
U2 - 10.1007/s10508-020-01903-8
DO - 10.1007/s10508-020-01903-8
M3 - Article
C2 - 34075504
AN - SCOPUS:85107387691
SN - 0004-0002
VL - 50
SP - 1713
EP - 1728
JO - Archives of Sexual Behavior
JF - Archives of Sexual Behavior
IS - 4
ER -