Abstract
Abbott amino-diol (2S,3R,4S)-2-amino-1-cyclohexyl-6-methyl heptane-3,4- diol 1, a main structural constituent of the orally active renin inhibitor Zankiren has been synthesized using Sharpless asymmetric aminohydroxylation as the key step.
Original language | English |
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Pages (from-to) | 4763-4768 |
Number of pages | 6 |
Journal | Tetrahedron |
Volume | 55 |
Issue number | 15 |
DOIs | |
State | Published - 9 Apr 1999 |