Abstract
In order to examine possible long-term effects of neonatal hyperthyroidism on catecholamine (CA) neural systems, mice receiving saline or thyroxine injections during the neonatal period were subsequently injected with d-amphetamine or saline immediately prior to testing for locomotor activity at 100 days of age. Thyroxine-treated males were more active than control males following amphetamine injections, but thyroxine-treated and control females did not differ in this regard. In general, the results suggest that neonatal hyperthyroidism may have long-lasting effects on CA function that, at least at the age tested, may be limited to the male mouse.
Original language | English |
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Pages (from-to) | 337-339 |
Number of pages | 3 |
Journal | Bulletin of the Psychonomic Society |
Volume | 18 |
Issue number | 6 |
DOIs | |
State | Published - Dec 1981 |